MK4MDD

Enriched GO by DAVID

The GO-enriched analysis was done by DAVID using 1239 MDD related genes from literature. GO terms with FDR < 0.05 were shown.

Biological Process (count: 355)
GO ID Name % P-value Fold Enrichment FDR Genes
GO:0007610 behavior 0.882089449 1.52E-38 3.550073807 2.83E-35 128 genes
GO:0019226 transmission of nerve impulse 0.751154297 1.87E-38 4.050967033 3.49E-35 109 genes
GO:0007268 synaptic transmission 0.682241059 1.48E-37 4.321347445 2.78E-34 99 genes
GO:0007267 cell-cell signaling 0.978567983 2.52E-35 3.078487179 4.72E-32 142 genes
GO:0010033 response to organic substance 1.047481221 8.85E-32 2.742259682 1.66E-28 152 genes
GO:0044057 regulation of system process 0.640893116 1.79E-31 3.91493652 3.34E-28 93 genes
GO:0009611 response to wounding 0.826958859 7.02E-28 2.945137881 1.31E-24 120 genes
GO:0009719 response to endogenous stimulus 0.682241059 1.15E-25 3.17965812 2.14E-22 99 genes
GO:0031644 regulation of neurological system process 0.399696782 2.34E-25 4.931020613 4.38E-22 58 genes
GO:0043067 regulation of programmed cell death 1.02680725 1.62E-24 2.3868795 3.02E-21 149 genes
GO:0042981 regulation of apoptosis 1.019915926 1.71E-24 2.394450823 3.20E-21 148 genes
GO:0010941 regulation of cell death 1.02680725 2.37E-24 2.37809344 4.43E-21 149 genes
GO:0007611 learning or memory 0.330783544 6.16E-24 5.624948025 1.15E-20 48 genes
GO:0050804 regulation of synaptic transmission 0.365240163 7.44E-24 5.069174208 1.39E-20 53 genes
GO:0007242 intracellular signaling cascade 1.357590793 8.90E-24 2.040219255 1.66E-20 197 genes
GO:0051969 regulation of transmission of nerve impulse 0.37902281 9.59E-24 4.866823653 1.79E-20 55 genes
GO:0042127 regulation of cell proliferation 0.992350631 1.48E-23 2.3800606 2.77E-20 144 genes
GO:0006873 cellular ion homeostasis 0.627110468 1.86E-23 3.164973262 3.47E-20 91 genes
GO:0055082 cellular chemical homeostasis 0.627110468 6.07E-23 3.115 1.13E-19 91 genes
GO:0044093 positive regulation of molecular function 0.799393564 8.79E-22 2.574901549 1.64E-18 116 genes
GO:0050801 ion homeostasis 0.640893116 9.20E-22 2.957739327 1.72E-18 93 genes
GO:0048878 chemical homeostasis 0.723589001 6.37E-21 2.667593149 1.19E-17 105 genes
GO:0019932 second-messenger-mediated signaling 0.454827372 1.25E-20 3.653224223 2.34E-17 66 genes
GO:0009725 response to hormone stimulus 0.585762525 1.83E-20 3.01268078 3.42E-17 85 genes
GO:0019725 cellular homeostasis 0.675349735 2.38E-20 2.735523275 4.45E-17 98 genes
GO:0043066 negative regulation of apoptosis 0.571979877 2.40E-20 3.049826163 4.49E-17 83 genes
GO:0032101 regulation of response to external stimulus 0.365240163 2.78E-20 4.335897436 5.19E-17 53 genes
GO:0014070 response to organic cyclic substance 0.317000896 2.98E-20 4.945073109 5.57E-17 46 genes
GO:0051046 regulation of secretion 0.413479429 4.20E-20 3.863670982 7.86E-17 60 genes
GO:0043069 negative regulation of programmed cell death 0.571979877 6.07E-20 3.007349475 1.14E-16 83 genes
GO:0042493 response to drug 0.427262077 6.26E-20 3.733689459 1.17E-16 62 genes
GO:0060548 negative regulation of cell death 0.571979877 7.29E-20 2.998995726 1.36E-16 83 genes
GO:0060341 regulation of cellular localization 0.454827372 2.72E-19 3.461724566 5.08E-16 66 genes
GO:0042592 homeostatic process 0.888980773 1.06E-18 2.234343952 1.99E-15 129 genes
GO:0051240 positive regulation of multicellular organismal process 0.441044725 2.20E-18 3.41185372 4.12E-15 64 genes
GO:0030005 "cellular di-, tri-valent inorganic cation homeostasis" 0.420370753 4.26E-18 3.495459166 7.97E-15 61 genes
GO:0030003 cellular cation homeostasis 0.447936049 4.46E-18 3.328740157 8.35E-15 65 genes
GO:0006874 cellular calcium ion homeostasis 0.372131486 5.17E-18 3.838335435 9.67E-15 54 genes
GO:0006875 cellular metal ion homeostasis 0.385914134 5.84E-18 3.716483516 1.09E-14 56 genes
GO:0055066 "di-, tri-valent inorganic cation homeostasis" 0.427262077 1.40E-17 3.374380431 2.62E-14 62 genes
GO:0055074 calcium ion homeostasis 0.372131486 1.88E-17 3.736252046 3.52E-14 54 genes
GO:0006928 cell motion 0.640893116 3.22E-17 2.546769231 6.01E-14 93 genes
GO:0055080 cation homeostasis 0.46861002 4.17E-17 3.092738031 7.79E-14 68 genes
GO:0009628 response to abiotic stimulus 0.544414582 4.85E-17 2.792412207 9.07E-14 79 genes
GO:0055065 metal ion homeostasis 0.385914134 5.21E-17 3.553320826 9.74E-14 56 genes
GO:0043085 positive regulation of catalytic activity 0.675349735 5.70E-17 2.451449704 2.11E-13 98 genes
GO:0048511 rhythmic process 0.296326924 1.06E-16 4.369771635 2.11E-13 43 genes
GO:0010647 positive regulation of cell communication 0.503066639 1.35E-16 2.886205284 2.11E-13 73 genes
GO:0051050 positive regulation of transport 0.399696782 1.52E-16 3.383166609 2.11E-13 58 genes
GO:0006954 inflammatory response 0.489283991 1.19E-15 2.841680473 2.29E-12 71 genes
GO:0007626 locomotory behavior 0.441044725 1.28E-15 3.038293094 2.49E-12 64 genes
GO:0050877 neurological system process 1.17152505 2.18E-15 1.827527018 4.15E-12 170 genes
GO:0008285 negative regulation of cell proliferation 0.516849287 2.92E-15 2.70242915 5.40E-12 75 genes
GO:0008284 positive regulation of cell proliferation 0.55819723 6.68E-15 2.544983278 1.25E-11 81 genes
GO:0042325 regulation of phosphorylation 0.599545173 1.02E-14 2.428474744 1.91E-11 87 genes
GO:0010243 response to organic nitrogen 0.192957067 1.93E-14 5.781196581 3.61E-11 28 genes
GO:0007166 cell surface receptor linked signal transduction 1.578113156 3.31E-14 1.604936174 6.19E-11 229 genes
GO:0019220 regulation of phosphate metabolic process 0.606436496 3.97E-14 2.360158604 7.41E-11 88 genes
GO:0051174 regulation of phosphorus metabolic process 0.606436496 3.97E-14 2.360158604 7.41E-11 88 genes
GO:0043523 regulation of neuron apoptosis 0.227413686 4.24E-14 4.769487179 7.93E-11 33 genes
GO:0019935 cyclic-nucleotide-mediated signaling 0.275652953 4.39E-14 4.002366864 8.22E-11 40 genes
GO:0030182 neuron differentiation 0.565088554 5.72E-14 2.435230067 1.07E-10 82 genes
GO:0001505 regulation of neurotransmitter levels 0.192957067 1.20E-13 5.436050517 2.25E-10 28 genes
GO:0048545 response to steroid hormone stimulus 0.337674867 1.21E-13 3.319671474 2.26E-10 49 genes
GO:0030808 regulation of nucleotide biosynthetic process 0.248087658 1.26E-13 4.257062937 2.36E-10 36 genes
GO:0030802 regulation of cyclic nucleotide biosynthetic process 0.248087658 1.26E-13 4.257062937 2.36E-10 36 genes
GO:0007568 aging 0.248087658 1.26E-13 4.257062937 2.36E-10 36 genes
GO:0032102 negative regulation of response to external stimulus 0.165391772 2.65E-13 6.243692308 4.95E-10 24 genes
GO:0030817 regulation of cAMP biosynthetic process 0.23430501 2.72E-13 4.378827113 5.09E-10 34 genes
GO:0045471 response to ethanol 0.186065743 2.73E-13 5.487620192 5.10E-10 27 genes
GO:0030799 regulation of cyclic nucleotide metabolic process 0.248087658 3.11E-13 4.144043567 5.81E-10 36 genes
GO:0007623 circadian rhythm 0.158500448 3.22E-13 6.503846154 6.01E-10 23 genes
GO:0048666 neuron development 0.46861002 3.86E-13 2.609212616 7.22E-10 68 genes
GO:0007612 learning 0.179174419 3.93E-13 5.636666667 7.36E-10 26 genes
GO:0051241 negative regulation of multicellular organismal process 0.303218248 4.00E-13 3.489868668 7.48E-10 44 genes
GO:0009991 response to extracellular stimulus 0.358348839 4.97E-13 3.074545455 9.30E-10 52 genes
GO:0030814 regulation of cAMP metabolic process 0.23430501 5.10E-13 4.293801344 9.53E-10 34 genes
GO:0007187 "G-protein signaling, coupled to cyclic nucleotide second messenger" 0.248087658 5.54E-13 4.071973244 1.04E-09 36 genes
GO:0009967 positive regulation of signal transduction 0.427262077 5.78E-13 2.733820078 1.08E-09 62 genes
GO:0006140 regulation of nucleotide metabolic process 0.248087658 7.36E-13 4.036870027 1.38E-09 36 genes
GO:0031279 regulation of cyclase activity 0.227413686 8.75E-13 4.335897436 1.64E-09 33 genes
GO:0048585 negative regulation of response to stimulus 0.227413686 1.19E-12 4.292538462 2.23E-09 33 genes
GO:0002697 regulation of immune effector process 0.227413686 1.62E-12 4.250038081 3.03E-09 33 genes
GO:0051339 regulation of lyase activity 0.227413686 1.62E-12 4.250038081 3.03E-09 33 genes
GO:0006916 anti-apoptosis 0.337674867 1.99E-12 3.094062733 3.73E-09 49 genes
GO:0045761 regulation of adenylate cyclase activity 0.220522362 2.05E-12 4.335897436 3.83E-09 32 genes
GO:0043524 negative regulation of neuron apoptosis 0.158500448 4.38E-12 5.866214178 8.19E-09 23 genes
GO:0031667 response to nutrient levels 0.32389222 5.34E-12 3.103358063 9.99E-09 47 genes
GO:0030030 cell projection organization 0.475501344 6.79E-12 2.438942308 1.27E-08 69 genes
GO:0008217 regulation of blood pressure 0.220522362 6.88E-12 4.162461538 1.29E-08 32 genes
GO:0006836 neurotransmitter transport 0.199848391 7.25E-12 4.544856348 1.36E-08 29 genes
GO:0007613 memory 0.137826476 8.88E-12 6.67061144 1.66E-08 20 genes
GO:0006952 defense response 0.668458411 1.01E-11 2.051619762 1.89E-08 97 genes