MK4MDD

Gene Report

Basic Information
Approved Symbol STX1A
Approved Name syntaxin 1A (brain)
Previous Symbol STX1
Symbol Alias HPC-1, p35-1
Location 7q11.2
Position chr7:73133962-73134017 (-)
External Links Entrez Gene: 6804
Ensembl: ENSG00000106089
UCSC: uc003tyx.3
HGNC ID: 11433
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between STX1A and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
Syntaxin 1A Tochigi, 2008 patients and normal controls Genes differentially expressed in major depression Genes differentially expressed in major depression
STX1A Carvalho LA, 2014 patients and normal controls FC=2; P-value=0.018 Thirty-four of the 47 monocyte inflammatory-related genes w...... Thirty-four of the 47 monocyte inflammatory-related genes were significantly upregulated and 2 were significantly downregulated as compared to controls More...

Positive relationships between STX1A and other components at different levels (count: 0) Help
Positive relationship network of STX1A in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between STX1A and MDD (count: 0)
Negative relationships between STX1A and other components at different levels (count: 0) Help
STX1A related SNPs in MK4MDD (count: 0)
STX1A related proteins in MK4MDD (count: 0)
STX1A related GO terms (count: 51)
STX1A related KEGG pathways (count: 1)
STX1A related BioCarta pathways (count: 0)
STX1A related Reactome pathways (count: 17)
STX1A related interactors from protein-protein interaction data in HPRD (count: 53)