MK4MDD

Gene Report

Basic Information
Approved Symbol SLC6A2
Approved Name solute carrier family 6 (neurotransmitter transporter), member 2
Previous Symbol NET1, NAT1, SLC6A5
Previous Name "solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2"
Symbol Alias NET
Name Alias "norepinephrine transporter"
Location 16q12.2
Position chr16:55739185-55740104 (+)
External Links Entrez Gene: 6530
Ensembl: ENSG00000103546
UCSC: uc021tio.1
HGNC ID: 11048
No. of Studies (Positive/Negative) 3(3/0) Help
Type Literature-origin; SNP mapped; Protein mapped

Positive relationships between SLC6A2 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
SLC6A2 Bosker, 2010 patients and normal controls P-value = 0.039 significantly more SNPs (19 out of 100; P = 0.039)than expec...... significantly more SNPs (19 out of 100; P = 0.039)than expected were associated while accounting for the linkage disequilibrium (LD) structure. More...
SLC6A2 Hahn, 2008 patients and normal controls OR = 4.15 (1.91-9.02) MPT analyses show significant associations of the norepineph...... MPT analyses show significant associations of the norepinephrine transporter (NET, SLC6A2) -182 T/C (rs2242446) with recurrent depression [odds ratio, OR = 4.15 (1.91-9.02)] More...

Positive relationships between SLC6A2 and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of SLC6A2 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between SLC6A2 and MDD (count: 0)
Negative relationships between SLC6A2 and other components at different levels (count: 0) Help
SLC6A2 related SNPs in MK4MDD (count: 1)
SLC6A2 related proteins in MK4MDD (count: 1)
SLC6A2 related GO terms (count: 16)
SLC6A2 related KEGG pathways (count: 0)
SLC6A2 related BioCarta pathways (count: 0)
SLC6A2 related Reactome pathways (count: 5)
SLC6A2 related interactors from protein-protein interaction data in HPRD (count: 2)