SNP Report

Name	rs2242446 dbSNP Ensembl
Location	Chrchr16:55690425(Forward)
Variant Alleles	C/T
Ancestral Allele	C
Annotation	5_prime_UTR_variant; intron_variant; upstream_gene_variant
Consequence to Transcript	5_prime_UTR_variant(ENST00000379906) intron_variant(ENST00000414754, ENST00000568529, ENST00000568655, ENST00000568943) upstream_gene_variant(ENST00000219833, ENST00000561820, ENST00000566163)
No. of Studies (Positive/Negative)	2 (2/0)

Reference	Research Type	Statistical Result	Relation Description
Bosker, 2010	patients and normal controls		Significance of candidate SNPs for MDD identified from the l...... Significance of candidate SNPs for MDD identified from the literature within the GAIN MDD GWAS More...
Hahn, 2008	patients and normal controls	odds ratio, OR = 4.15 (1.91-9.02)	MPT analyses show significant associations of the norepineph...... MPT analyses show significant associations of the norepinephrine transporter (NET, SLC6A2) -182 T/C (rs2242446) with recurrent depression [odds ratio, OR = 4.15 (1.91-9.02)] More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Approved Symbol	Approved Name	Type	No. of Studies (Positive/Negative)
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	Literature-origin; SNP mapped; Protein mapped	3(3/0)