Reactome Pathway Report
Basic Information
| ID |
|
| Name |
norepinephrine neurotransmitter_release_cycle
|
| Description |
Noradrenalin release cycle consists of reacidification of the empty clathrin sculpted monoamine transport vesicle, loading of dopamine into reacidified clathrin coated monamine transport vesicle, conversion of dopamine into Noradrenalin, docking and priming of the noradrenalin synaptic veiscle and then release of noradrenalin synaptic vesicle. In the peripheral nervous system in the peripheral nervous system noradrenalin is stored in large and small dense vesicles and is realesed from large vesicles.
|
REACT_15418 related genes in MK4MDD (count: 7)
| Approved Symbol |
Approved Name |
Type |
No. of Studies (Positive/Negative) |
| CPLX1 |
complexin 1 |
Protein mapped
|
0(0/0) |
| MAOA |
monoamine oxidase A |
Literature-origin; SNP mapped; Protein mapped
|
12(9/3) |
| SLC18A2 |
solute carrier family 18 (vesicular monoamine), member 2 |
Literature-origin; Protein mapped
|
1(1/0) |
| RAB3A |
RAB3A, member RAS oncogene family |
Literature-origin
|
1(1/0) |
| STX1A |
syntaxin 1A (brain) |
Literature-origin
|
1(1/0) |
| DBH |
dopamine beta-hydroxylase (dopamine beta-monooxygenase) |
Literature-origin; Protein mapped
|
1(1/0) |
| SNAP25 |
synaptosomal-associated protein, 25kDa |
Literature-origin; Protein mapped
|
1(1/0) |
