MK4MDD

Gene Report

Basic Information
Approved Symbol SLC6A3
Approved Name solute carrier family 6 (neurotransmitter transporter), member 3
Previous Symbol DAT1
Previous Name "solute carrier family 6 (neurotransmitter transporter, dopamine), member 3", "dopamine transporter 1"
Symbol Alias DAT
Name Alias "dopamine transporter"
Location 5p15.3
Position chr5:1445463-1445543 (-)
External Links Entrez Gene: 6531
Ensembl: ENSG00000142319
UCSC: uc003jck.3
HGNC ID: 11049
No. of Studies (Positive/Negative) 3(2/1) Help
Type Literature-origin; Protein mapped

Positive relationships between SLC6A3 and MDD (count: 0)
Positive relationships between SLC6A3 and other components at different levels (count: 2) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of SLC6A3 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between SLC6A3 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description
dopamine transporter gene (DAT1) Huang, 2011 patients and normal controls Several association tendencies were found between DAT1 and m...... Several association tendencies were found between DAT1 and major depression More...

Negative relationships between SLC6A3 and other components at different levels (count: 0) Help
SLC6A3 related SNPs in MK4MDD (count: 0)
SLC6A3 related proteins in MK4MDD (count: 1)
SLC6A3 related GO terms (count: 44)
SLC6A3 related KEGG pathways (count: 1)
SLC6A3 related BioCarta pathways (count: 0)
SLC6A3 related Reactome pathways (count: 6)
SLC6A3 related interactors from protein-protein interaction data in HPRD (count: 7)