MK4MDD

Gene Ontology Report

Basic Information
ID GO:0042493
Name response to drug
Type biological process

GO:0042493 related genes in MK4MDD (count: 56)
Approved Symbol Approved Name Type No. of Studies (Positive/Negative) Evidence
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) Literature-origin; Protein mapped 2(2/0) IEA
APOD apolipoprotein D Literature-origin; Protein mapped 1(1/0) ISS
P2RX7 purinergic receptor P2X, ligand-gated ion channel, 7 Literature-origin; SNP mapped 6(5/1) IEA
FOSB FBJ murine osteosarcoma viral oncogene homolog B Literature-origin 1(1/0) IEA
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) Literature-origin; SNP mapped 5(1/4) IEA
THRA thyroid hormone receptor, alpha Literature-origin 1(1/0) IEA
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) Literature-origin 1(1/0) IEA
DRD1 dopamine receptor D1 Literature-origin; Protein mapped 2(2/0) ISS
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C Literature-origin 2(2/0) TAS[9405678]
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 Literature-origin; Protein mapped 56(44/12) IEA
BAX BCL2-associated X protein Literature-origin 1(1/0) IEA
IFNG interferon, gamma Literature-origin; Protein mapped 1(1/0) IEA
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 Literature-origin; Protein mapped 6(3/3) IEA
AK4 adenylate kinase 4 Literature-origin 1(1/0) IEA
IGFBP2 insulin-like growth factor binding protein 2, 36kDa Literature-origin 1(1/0) IEA
JUN jun proto-oncogene Literature-origin 1(1/0) IBA
GCLM glutamate-cysteine ligase, modifier subunit Literature-origin 1(1/0) IDA[9895302]
SST somatostatin Literature-origin; Protein mapped 3(3/0) IEA
HDAC2 histone deacetylase 2 Literature-origin 1(1/0) IEA
PTK2B protein tyrosine kinase 2 beta Literature-origin 2(2/0) IEA
FOS FBJ murine osteosarcoma viral oncogene homolog Literature-origin; Protein mapped 1(1/0) IEA
IL10 interleukin 10 Literature-origin; Protein mapped 4(2/2) IEA
GAL galanin/GMAP prepropeptide Literature-origin 2(1/1) IEA
IL6 interleukin 6 (interferon, beta 2) Literature-origin; Protein mapped 2(1/1) IEA
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Literature-origin; SNP mapped; Protein mapped 11(7/4) IDA[15862800|18703043]
GNAS GNAS complex locus Literature-origin 1(0/1) IEA
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 Literature-origin; Protein mapped 3(2/1) IEA
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta Literature-origin 2(1/1) IEA
MCM7 minichromosome maintenance complex component 7 Literature-origin 1(1/0) IEA
NPC1 Niemann-Pick disease, type C1 Literature-origin 1(1/0) IEA
DVL3 dishevelled segment polarity protein 3 Literature-origin 1(1/0) IEA
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A Literature-origin; Protein mapped 2(2/0) IEA
HDAC5 histone deacetylase 5 Literature-origin 3(3/0) IEA
PTN pleiotrophin Literature-origin 1(1/0) IEA
APC adenomatous polyposis coli Literature-origin 1(1/0) IEA
DRD2 dopamine receptor D2 Literature-origin; Protein mapped 5(3/2) IBA; ISS
BDNF brain-derived neurotrophic factor Literature-origin; SNP mapped; Protein mapped 28(19/9) IEA
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit Literature-origin 1(1/0) IEA
CCND1 cyclin D1 Literature-origin 1(1/0) IEP[18291362]
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 Literature-origin 1(0/1) TAS[7912658]
PTPRM protein tyrosine phosphatase, receptor type, M Literature-origin 1(1/0) IDA[18566238]
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor Literature-origin 1(1/0) IEA
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide Literature-origin; Protein mapped 1(1/0) IEA
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 Literature-origin 1(1/0) IMP[17875758]
LTA lymphotoxin alpha Literature-origin 2(1/1) IEA
GAD1 glutamate decarboxylase 1 (brain, 67kDa) Literature-origin; Protein mapped 3(2/1) IEA
CAT catalase Literature-origin 2(1/1) IEA
COL1A1 collagen, type I, alpha 1 Literature-origin 1(1/0) IEA
OXTR oxytocin receptor Literature-origin 1(1/0) IEA
GSK3B glycogen synthase kinase 3 beta Literature-origin; Protein mapped 7(6/1) IEA
COMT catechol-O-methyltransferase Literature-origin; SNP mapped 11(8/3) IEA
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) Literature-origin 1(1/0) IEA
PDE3A phosphodiesterase 3A, cGMP-inhibited Literature-origin 1(1/0) IEA
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 Literature-origin; SNP mapped 3(2/1) TAS[3022150]
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Literature-origin; SNP mapped 4(3/1) IDA[18703043]
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 Literature-origin; Protein mapped 4(3/1) IEA