MK4MDD

Gene Report

Basic Information
Approved Symbol GNAS
Approved Name GNAS complex locus
Previous Symbol GNAS1
Previous Name "guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1"
Symbol Alias NESP55, NESP, GNASXL, GPSA, SCG6
Name Alias "secretogranin VI"
Location 20q13.2-q13.3
Position chr20:57485885-57486247 (+)
External Links Entrez Gene: 2778
Ensembl: ENSG00000087460
UCSC: uc002xzw.3
HGNC ID: 4392
No. of Studies (Positive/Negative) 1(0/1) Help
Type Literature-origin

Positive relationships between GNAS and MDD (count: 0)
Positive relationships between GNAS and other components at different levels (count: 0) Help
Positive relationship network of GNAS in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between GNAS and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description
stimulatory alpha subunit of G-proteins Zill P, 2002 Patients and nomal controls There was no evidence for an association between the invest...... There was no evidence for an association between the investigated polymorphism in the G(alpha)(s) gene and major depression, as well as to treatment response. More...

Negative relationships between GNAS and other components at different levels (count: 0) Help
GNAS related SNPs in MK4MDD (count: 0)
GNAS related proteins in MK4MDD (count: 0)
GNAS related GO terms (count: 75)
GNAS related KEGG pathways (count: 10)
GNAS related BioCarta pathways (count: 13)
GNAS related Reactome pathways (count: 11)
GNAS related interactors from protein-protein interaction data in HPRD (count: 24)