MK4MDD

Gene Report

Basic Information
Approved Symbol DRD2
Approved Name dopamine receptor D2
Location 11q22-q23
Position chr11:113346380-113346413 (-)
External Links Entrez Gene: 1813
Ensembl: ENSG00000149295
UCSC: uc001poa.4
HGNC ID: 3023
No. of Studies (Positive/Negative) 5(3/2) Help
Type Literature-origin; Protein mapped

Positive relationships between DRD2 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
DRD2 Koks, 2006 patients and normal controls SNPs in CCKAR, DRD1, DRD2, and HTR2C genes showed nominally ...... SNPs in CCKAR, DRD1, DRD2, and HTR2C genes showed nominally significant associations with MDD. More...
DRD2 Wang Y, 2012 patients and normal controls The results suggest that the DRD2 gene may play a role on MD...... The results suggest that the DRD2 gene may play a role on MDD susceptibility and the onset-time of antidepressant response More...

Positive relationships between DRD2 and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of DRD2 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between DRD2 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description
DRD2 He M, 2013 patients and normal controls However, we could detect no evidence of genetic association ...... However, we could detect no evidence of genetic association between 3 markers in DRD2 and major depressive disorder in the Chinese Han population More...

Negative relationships between DRD2 and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


DRD2 related SNPs in MK4MDD (count: 0)
DRD2 related proteins in MK4MDD (count: 1)
DRD2 related GO terms (count: 117)
DRD2 related KEGG pathways (count: 2)
DRD2 related BioCarta pathways (count: 1)
DRD2 related Reactome pathways (count: 5)
DRD2 related interactors from protein-protein interaction data in HPRD (count: 19)