MK4MDD

KEGG Pathway Report

Basic Information
ID hsa04080
Name neuroactive ligand_receptor_interaction
Brief Description Neuroactive ligand-receptor interaction
Full Description  

hsa04080 related genes in MK4MDD (count: 82)
Approved Symbol Approved Name Type No. of Studies (Positive/Negative)
HCRTR1 hypocretin (orexin) receptor 1 Literature-origin; SNP mapped 2(2/0)
CRHR2 corticotropin releasing hormone receptor 2 Literature-origin; SNP mapped 1(0/1)
CCKAR cholecystokinin A receptor Literature-origin 1(1/0)
CHRM2 cholinergic receptor, muscarinic 2 Literature-origin; Protein mapped 2(1/1)
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) Literature-origin; SNP mapped 1(1/0)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) Literature-origin 1(1/0)
CRHR1 corticotropin releasing hormone receptor 1 Literature-origin; SNP mapped; Protein mapped 7(6/1)
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Literature-origin; SNP mapped; Protein mapped 11(7/4)
S1PR1 sphingosine-1-phosphate receptor 1 Literature-origin 1(1/0)
GRIA2 glutamate receptor, ionotropic, AMPA 2 Literature-origin 1(1/0)
GRM3 glutamate receptor, metabotropic 3 Literature-origin; Protein mapped 4(3/1)
CNR2 cannabinoid receptor 2 (macrophage) Literature-origin 1(1/0)
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B Literature-origin; Protein mapped 2(2/0)
AVPR1B arginine vasopressin receptor 1B Literature-origin; Protein mapped 1(1/0)
GRIK5 glutamate receptor, ionotropic, kainate 5 Literature-origin 1(1/0)
OPRM1 opioid receptor, mu 1 Literature-origin; SNP mapped; Protein mapped 2(1/1)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 Literature-origin; Protein mapped 1(1/0)
PTH1R parathyroid hormone 1 receptor Literature-origin 1(1/0)
DRD3 dopamine receptor D3 SNP mapped; Protein mapped 0(0/0)
SSTR5 somatostatin receptor 5 Literature-origin 1(1/0)
CCKBR cholecystokinin B receptor Literature-origin 2(2/0)
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 Literature-origin 3(2/1)
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled Literature-origin; Protein mapped 5(4/1)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 Literature-origin 2(2/0)
DRD1 dopamine receptor D1 Literature-origin; Protein mapped 2(2/0)
GRIA3 glutamate receptor, ionotropic, AMPA 3 Literature-origin; Protein mapped 3(2/1)
HRH1 histamine receptor H1 Protein mapped 0(0/0)
OXTR oxytocin receptor Literature-origin 1(1/0)
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled Literature-origin; Protein mapped 15(11/4)
PRLR prolactin receptor Literature-origin 1(1/0)
GRIA1 glutamate receptor, ionotropic, AMPA 1 Literature-origin; Protein mapped 1(1/0)
NMUR1 neuromedin U receptor 1 Literature-origin 1(1/0)
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 Protein mapped 0(0/0)
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled Literature-origin 1(1/0)
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 Literature-origin 1(1/0)
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 Literature-origin; Protein mapped 2(2/0)
GABRD gamma-aminobutyric acid (GABA) A receptor, delta Literature-origin 1(1/0)
GPR50 G protein-coupled receptor 50 Literature-origin 1(1/0)
GRID2 glutamate receptor, ionotropic, delta 2 Literature-origin 1(1/0)
LEPR leptin receptor Literature-origin; Protein mapped 3(3/0)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 Literature-origin; Protein mapped 1(1/0)
NTSR2 neurotensin receptor 2 Literature-origin 1(1/0)
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 Literature-origin 1(1/0)
LPAR1 lysophosphatidic acid receptor 1 Literature-origin 2(2/0)
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 Protein mapped 0(0/0)
PRL prolactin Protein mapped 0(0/0)
F2 coagulation factor II (thrombin) Protein mapped 0(0/0)
BDKRB1 bradykinin receptor B1 Protein mapped 0(0/0)
ADRA2A adrenoceptor alpha 2A Literature-origin; Protein mapped 2(2/0)
GRIK3 glutamate receptor, ionotropic, kainate 3 Literature-origin 1(1/0)
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 Literature-origin 1(1/0)
FSHB follicle stimulating hormone, beta polypeptide Protein mapped 0(0/0)
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A SNP mapped 0(0/0)
ADRA2C adrenoceptor alpha 2C Protein mapped 0(0/0)
TSHB thyroid stimulating hormone, beta Protein mapped 0(0/0)
GPR35 G protein-coupled receptor 35 Protein mapped 0(0/0)
DRD4 dopamine receptor D4 Literature-origin 2(0/2)
BDKRB2 bradykinin receptor B2 SNP mapped 0(0/0)
GH1 growth hormone 1 Protein mapped 0(0/0)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Literature-origin; Protein mapped 8(8/0)
ADRB2 adrenoceptor beta 2, surface Literature-origin 1(1/0)
NPY1R neuropeptide Y receptor Y1 Literature-origin 1(1/0)
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A Literature-origin; Protein mapped 2(2/0)
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled Literature-origin 1(1/0)
GRIK2 glutamate receptor, ionotropic, kainate 2 Literature-origin 1(0/1)
GLRB glycine receptor, beta Literature-origin 1(1/0)
CNR1 cannabinoid receptor 1 (brain) Literature-origin; SNP mapped; Protein mapped 4(3/1)
THRA thyroid hormone receptor, alpha Literature-origin 1(1/0)
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled Literature-origin 2(0/2)
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon Protein mapped 0(0/0)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 Literature-origin; Protein mapped 1(1/0)
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 Literature-origin 1(1/0)
GRM5 glutamate receptor, metabotropic 5 Protein mapped 0(0/0)
GRM2 glutamate receptor, metabotropic 2 Protein mapped 0(0/0)
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 Literature-origin 2(2/0)
DRD2 dopamine receptor D2 Literature-origin; Protein mapped 5(3/2)
EDNRB endothelin receptor type B Literature-origin 1(1/0)
LEP leptin Protein mapped 0(0/0)
GRM1 glutamate receptor, metabotropic 1 Literature-origin 2(2/0)
P2RX7 purinergic receptor P2X, ligand-gated ion channel, 7 Literature-origin; SNP mapped 6(5/1)
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled Literature-origin; SNP mapped 4(3/1)
GALR2 galanin receptor 2 Literature-origin 1(1/0)