MK4MDD

Gene Report

Basic Information
Approved Symbol HCRTR1
Approved Name hypocretin (orexin) receptor 1
Symbol Alias OX1R
Location 1p33
Position chr1:32092947-32093214 (+)
External Links Entrez Gene: 3061
Ensembl: ENSG00000121764
UCSC: uc009vtx.2
HGNC ID: 4848
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin; SNP mapped

Positive relationships between HCRTR1 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
HCRTR1 Rainero I, 2011 Patients and nomal controls p<0.0001 we found a significant association between HCRTR1 haplotype...... we found a significant association between HCRTR1 haplotypes and the disease (permutation p<0.0001) More...
Orexin A Rotter, 2011 patients and normal controls T=1.53; df=39; P-value=0.135 There was a measurable difference between Orexin A expressio...... There was a measurable difference between Orexin A expression on admission in comparison to the Orexin mRNA expression in the healthy control group (T=1.53; df=39; p=0.135) that failed to reach statistical significance. More...

Positive relationships between HCRTR1 and other components at different levels (count: 5) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of HCRTR1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between HCRTR1 and MDD (count: 0)
Negative relationships between HCRTR1 and other components at different levels (count: 0) Help
HCRTR1 related SNPs in MK4MDD (count: 1)
HCRTR1 related proteins in MK4MDD (count: 0)
HCRTR1 related GO terms (count: 13)
HCRTR1 related KEGG pathways (count: 1)
HCRTR1 related BioCarta pathways (count: 0)
HCRTR1 related Reactome pathways (count: 5)
HCRTR1 related interactors from protein-protein interaction data in HPRD (count: 2)