Reactome Pathway Report
Basic Information
ID |
|
Name |
peptide ligand_binding_receptors
|
Description |
These receptors, a subset of the Class A/1 (Rhodopsin-like) family, all bind peptide ligands which include the chemokines, opioids and somatostatins.
|
REACT_14819 related genes in MK4MDD (count: 28)
Approved Symbol |
Approved Name |
Type |
No. of Studies (Positive/Negative) |
GAL |
galanin/GMAP prepropeptide |
Literature-origin; SNP mapped
|
2(1/1) |
HCRTR1 |
hypocretin (orexin) receptor 1 |
Literature-origin; SNP mapped
|
2(2/0) |
AGT |
angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
Protein mapped
|
0(0/0) |
AVPR1B |
arginine vasopressin receptor 1B |
Literature-origin; Protein mapped
|
1(1/0) |
SSTR5 |
somatostatin receptor 5 |
Literature-origin
|
1(1/0) |
OPRM1 |
opioid receptor, mu 1 |
Literature-origin; Protein mapped
|
1(1/0) |
EDN1 |
endothelin 1 |
Literature-origin
|
1(1/0) |
CCL2 |
chemokine (C-C motif) ligand 2 |
Literature-origin; SNP mapped; Protein mapped
|
2(1/1) |
CCKBR |
cholecystokinin B receptor |
Literature-origin
|
2(2/0) |
C3 |
complement component 3 |
Protein mapped
|
0(0/0) |
TACR1 |
tachykinin receptor 1 |
SNP mapped
|
0(0/0) |
F2 |
coagulation factor II (thrombin) |
Protein mapped
|
0(0/0) |
PROKR2 |
prokineticin receptor 2 |
Literature-origin
|
1(1/0) |
IL8 |
interleukin 8 |
Literature-origin
|
1(1/0) |
PROK2 |
prokineticin 2 |
Literature-origin
|
1(1/0) |
PENK |
proenkephalin |
Literature-origin
|
1(1/0) |
OXT |
oxytocin/neurophysin I prepropeptide |
Protein mapped
|
0(0/0) |
NPY |
neuropeptide Y |
Literature-origin; SNP mapped; Protein mapped
|
6(5/1) |
BDKRB2 |
bradykinin receptor B2 |
SNP mapped
|
0(0/0) |
POMC |
proopiomelanocortin |
Protein mapped
|
0(0/0) |
CXCR1 |
chemokine (C-X-C motif) receptor 1 |
Protein mapped
|
0(0/0) |
MC1R |
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
Literature-origin; SNP mapped
|
1(1/0) |
BDKRB1 |
bradykinin receptor B1 |
Protein mapped
|
0(0/0) |
GALR2 |
galanin receptor 2 |
Literature-origin
|
1(1/0) |
PDYN |
prodynorphin |
SNP mapped; Protein mapped
|
0(0/0) |
TAC1 |
tachykinin, precursor 1 |
Literature-origin; Protein mapped
|
2(2/0) |
SST |
somatostatin |
Literature-origin; Protein mapped
|
2(2/0) |
CCKAR |
cholecystokinin A receptor |
Literature-origin
|
1(1/0) |