Reactome Pathway Report

Basic Information
| ID |
|
| Name |
peptide ligand_binding_receptors
|
| Description |
These receptors, a subset of the Class A/1 (Rhodopsin-like) family, all bind peptide ligands which include the chemokines, opioids and somatostatins.
|
REACT_14819 related genes in MK4MDD (count: 28)
| Approved Symbol |
Approved Name |
Type |
No. of Studies (Positive/Negative) |
| GAL |
galanin/GMAP prepropeptide |
Literature-origin; SNP mapped
|
2(1/1) |
| HCRTR1 |
hypocretin (orexin) receptor 1 |
Literature-origin; SNP mapped
|
2(2/0) |
| AGT |
angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
Protein mapped
|
0(0/0) |
| AVPR1B |
arginine vasopressin receptor 1B |
Literature-origin; Protein mapped
|
1(1/0) |
| SSTR5 |
somatostatin receptor 5 |
Literature-origin
|
1(1/0) |
| OPRM1 |
opioid receptor, mu 1 |
Literature-origin; Protein mapped
|
1(1/0) |
| EDN1 |
endothelin 1 |
Literature-origin
|
1(1/0) |
| CCL2 |
chemokine (C-C motif) ligand 2 |
Literature-origin; SNP mapped; Protein mapped
|
2(1/1) |
| CCKBR |
cholecystokinin B receptor |
Literature-origin
|
2(2/0) |
| C3 |
complement component 3 |
Protein mapped
|
0(0/0) |
| TACR1 |
tachykinin receptor 1 |
SNP mapped
|
0(0/0) |
| F2 |
coagulation factor II (thrombin) |
Protein mapped
|
0(0/0) |
| PROKR2 |
prokineticin receptor 2 |
Literature-origin
|
1(1/0) |
| IL8 |
interleukin 8 |
Literature-origin
|
1(1/0) |
| PROK2 |
prokineticin 2 |
Literature-origin
|
1(1/0) |
| PENK |
proenkephalin |
Literature-origin
|
1(1/0) |
| OXT |
oxytocin/neurophysin I prepropeptide |
Protein mapped
|
0(0/0) |
| NPY |
neuropeptide Y |
Literature-origin; SNP mapped; Protein mapped
|
6(5/1) |
| BDKRB2 |
bradykinin receptor B2 |
SNP mapped
|
0(0/0) |
| POMC |
proopiomelanocortin |
Protein mapped
|
0(0/0) |
| CXCR1 |
chemokine (C-X-C motif) receptor 1 |
Protein mapped
|
0(0/0) |
| MC1R |
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
Literature-origin; SNP mapped
|
1(1/0) |
| BDKRB1 |
bradykinin receptor B1 |
Protein mapped
|
0(0/0) |
| GALR2 |
galanin receptor 2 |
Literature-origin
|
1(1/0) |
| PDYN |
prodynorphin |
SNP mapped; Protein mapped
|
0(0/0) |
| TAC1 |
tachykinin, precursor 1 |
Literature-origin; Protein mapped
|
2(2/0) |
| SST |
somatostatin |
Literature-origin; Protein mapped
|
2(2/0) |
| CCKAR |
cholecystokinin A receptor |
Literature-origin
|
1(1/0) |