MK4MDD

Gene Report

Basic Information
Approved Symbol TAC1
Approved Name tachykinin, precursor 1
Previous Symbol TAC2, NKNA
Previous Name "tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)"
Symbol Alias NPK
Name Alias "substance K", "substance P", "neurokinin 1", "neurokinin 2", "neuromedin L", "neurokinin alpha", "neuropeptide K", "neuropeptide gamma", "preprotachykinin"
Location 7q21-q22
Position chr7:97369233-97369784 (+)
External Links Entrez Gene: 6863
Ensembl: ENSG00000006128
UCSC: uc003uop.4
HGNC ID: 11517
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin; Protein mapped

Positive relationships between TAC1 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
TAC1 Guilloux JP, 2012 patients and normal controls genes significantly affected in female MDD subjects genes significantly affected in female MDD subjects

Positive relationships between TAC1 and other components at different levels (count: 4) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of TAC1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between TAC1 and MDD (count: 0)
Negative relationships between TAC1 and other components at different levels (count: 0) Help
TAC1 related SNPs in MK4MDD (count: 0)
TAC1 related proteins in MK4MDD (count: 1)
TAC1 related GO terms (count: 44)
TAC1 related KEGG pathways (count: 0)
TAC1 related BioCarta pathways (count: 0)
TAC1 related Reactome pathways (count: 5)
TAC1 related interactors from protein-protein interaction data in HPRD (count: 7)