Reactome Pathway Report

Basic Information

ID
Name	class a1_rhodopsin_like_receptors
Description	Rhodopsin-like receptors. They represent members which include hormone, light and neurotransmitter receptors and encompass a wide range of functions including many autocrine, paracrine and endocrine processes.

REACT_14828 related genes in MK4MDD (count: 51)

Approved Symbol	Approved Name	Type	No. of Studies (Positive/Negative)
HCRTR1	hypocretin (orexin) receptor 1	Literature-origin; SNP mapped	2(2/0)
HTR2A	5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled	Literature-origin; SNP mapped; Protein mapped	9(7/2)
DRD1	dopamine receptor D1	Literature-origin; Protein mapped	2(2/0)
HTR5A	5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled	Literature-origin	1(0/1)
AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	Protein mapped	0(0/0)
AVPR1B	arginine vasopressin receptor 1B	Literature-origin; Protein mapped	1(1/0)
ADRB2	adrenoceptor beta 2, surface	Literature-origin	1(1/0)
EDN1	endothelin 1	Literature-origin	1(1/0)
CCKBR	cholecystokinin B receptor	Literature-origin	2(2/0)
TACR1	tachykinin receptor 1	SNP mapped	0(0/0)
LPAR1	lysophosphatidic acid receptor 1	Literature-origin	1(1/0)
FSHB	follicle stimulating hormone, beta polypeptide	Protein mapped	0(0/0)
F2	coagulation factor II (thrombin)	Protein mapped	0(0/0)
DRD4	dopamine receptor D4	Literature-origin	2(0/2)
TSHB	thyroid stimulating hormone, beta	Protein mapped	0(0/0)
IL8	interleukin 8	Literature-origin	1(1/0)
OXT	oxytocin/neurophysin I prepropeptide	Protein mapped	0(0/0)
CNR1	cannabinoid receptor 1 (brain)	Literature-origin; SNP mapped; Protein mapped	3(3/0)
HTR1A	5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled	Literature-origin; SNP mapped; Protein mapped	13(11/2)
BDKRB2	bradykinin receptor B2	SNP mapped	0(0/0)
CXCR1	chemokine (C-X-C motif) receptor 1	Protein mapped	0(0/0)
MC1R	melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)	Literature-origin; SNP mapped	1(1/0)
BDKRB1	bradykinin receptor B1	Protein mapped	0(0/0)
TAC1	tachykinin, precursor 1	Literature-origin; Protein mapped	2(2/0)
HTR4	5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled	Literature-origin	1(1/0)
SST	somatostatin	Literature-origin; Protein mapped	2(2/0)
CCKAR	cholecystokinin A receptor	Literature-origin	1(1/0)
DRD2	dopamine receptor D2	Literature-origin; Protein mapped	4(3/1)
DRD3	dopamine receptor D3	SNP mapped; Protein mapped	0(0/0)
CNR2	cannabinoid receptor 2 (macrophage)	Literature-origin	1(1/0)
ADRA2A	adrenoceptor alpha 2A	Literature-origin; Protein mapped	2(2/0)
GAL	galanin/GMAP prepropeptide	Literature-origin; SNP mapped	2(1/1)
HTR1D	5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled	Literature-origin	1(1/0)
SSTR5	somatostatin receptor 5	Literature-origin	1(1/0)
OPRM1	opioid receptor, mu 1	Literature-origin; Protein mapped	1(1/0)
CCL2	chemokine (C-C motif) ligand 2	Literature-origin; SNP mapped; Protein mapped	2(1/1)
LPAR2	lysophosphatidic acid receptor 2	SNP mapped	0(0/0)
C3	complement component 3	Protein mapped	0(0/0)
CHRM2	cholinergic receptor, muscarinic 2	Literature-origin; SNP mapped; Protein mapped	2(1/1)
PROKR2	prokineticin receptor 2	Literature-origin	1(1/0)
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled	Literature-origin; SNP mapped; Protein mapped	5(4/1)
PROK2	prokineticin 2	Literature-origin	1(1/0)
PENK	proenkephalin	Literature-origin	1(1/0)
NPY	neuropeptide Y	Literature-origin; SNP mapped; Protein mapped	6(5/1)
POMC	proopiomelanocortin	Protein mapped	0(0/0)
ADRA2C	adrenoceptor alpha 2C	Protein mapped	0(0/0)
P2RY12	purinergic receptor P2Y, G-protein coupled, 12	Literature-origin	1(1/0)
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled	Literature-origin; SNP mapped	4(3/1)
GALR2	galanin receptor 2	Literature-origin	1(1/0)
PDYN	prodynorphin	SNP mapped; Protein mapped	0(0/0)
HRH1	histamine receptor H1	Protein mapped	0(0/0)