MK4MDD

Gene Report

Basic Information
Approved Symbol LPAR1
Approved Name lysophosphatidic acid receptor 1
Previous Symbol EDG2
Previous Name "endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2"
Symbol Alias edg-2, rec.1.3, vzg-1, Gpcr26, Mrec1.3, LPA1, GPR26
Location 9q
Position chr9:113801150-113801523 (-)
External Links Entrez Gene: 1902
Ensembl: ENSG00000198121
UCSC: uc004bfc.3
HGNC ID: 3166
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between LPAR1 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
EDG2 Aston, 2005 patients and normal controls Genes altered in major depressive disorder Genes altered in major depressive disorder
EDG2 Tomita H, 2013 patients and normal controls GPLS genes significantly dysregulated in anterior cingulate ...... GPLS genes significantly dysregulated in anterior cingulate cortex by microarray More...

Positive relationships between LPAR1 and other components at different levels (count: 0) Help
Positive relationship network of LPAR1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between LPAR1 and MDD (count: 0)
Negative relationships between LPAR1 and other components at different levels (count: 0) Help
LPAR1 related SNPs in MK4MDD (count: 0)
LPAR1 related proteins in MK4MDD (count: 0)
LPAR1 related GO terms (count: 40)
LPAR1 related KEGG pathways (count: 2)
LPAR1 related BioCarta pathways (count: 1)
LPAR1 related Reactome pathways (count: 5)
LPAR1 related interactors from protein-protein interaction data in HPRD (count: 4)