Gene Ontology Report

Basic Information
ID GO:0007186
Name G-protein coupled receptor signaling pathway
Type biological process

GO:0007186 related genes in MK4MDD (count: 51)
Approved Symbol Approved Name Type No. of Studies (Positive/Negative) Evidence
CXCL3 chemokine (C-X-C motif) ligand 3 Literature-origin 1(1/0) IBA
PROK2 prokineticin 2 Literature-origin 1(1/0) NAS[11259612]
SST somatostatin Literature-origin; Protein mapped 3(3/0) TAS[8405411]
INS insulin Literature-origin; Protein mapped 1(1/0) IDA[9092559]
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled Literature-origin; Protein mapped 15(11/4) IMP[22957663]
FZD9 frizzled class receptor 9 Literature-origin 1(0/1) IEA
S1PR1 sphingosine-1-phosphate receptor 1 Literature-origin 1(1/0) TAS[8626678]
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 Literature-origin 1(1/0) IEA
IL8 interleukin 8 Literature-origin; Protein mapped 2(2/0) TAS[8381837]
PTPN6 protein tyrosine phosphatase, non-receptor type 6 Literature-origin 1(1/0) TAS[7781604]
GPRC5B G protein-coupled receptor, class C, group 5, member B Literature-origin 3(3/0) IEA
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled Literature-origin 2(0/2) TAS[7988681]
ADRA2A adrenoceptor alpha 2A Literature-origin; Protein mapped 2(2/0) ISS[19965390]
GNG3 guanine nucleotide binding protein (G protein), gamma 3 Literature-origin 1(1/0) IEA
PROKR2 prokineticin receptor 2 Literature-origin 1(1/0) IBA
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 Literature-origin; SNP mapped 2(2/0) TAS[2107550]
LPAR1 lysophosphatidic acid receptor 1 Literature-origin 2(2/0) TAS[8922387]
CCL7 chemokine (C-C motif) ligand 7 Literature-origin 1(1/0) IBA
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 Literature-origin; Protein mapped 1(1/0) TAS[9872316]
CALM2 calmodulin 2 (phosphorylase kinase, delta) Literature-origin 1(1/0) TAS[10899953]
P2RY12 purinergic receptor P2Y, G-protein coupled, 12 Literature-origin 1(1/0) IDA[11104774]
APLP2 amyloid beta (A4) precursor-like protein 2 Literature-origin 1(1/0) NAS[8220435]
RORB RAR-related orphan receptor B Literature-origin 1(0/1) IEA
AVPR1B arginine vasopressin receptor 1B Literature-origin; Protein mapped 1(1/0) IEA
CHRM2 cholinergic receptor, muscarinic 2 Literature-origin; Protein mapped 2(1/1) TAS[9603968]
CCL2 chemokine (C-C motif) ligand 2 Literature-origin; Protein mapped 3(2/1) TAS[10542238]
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 Literature-origin 2(2/0) TAS[1733949]
KCNK2 potassium channel, subfamily K, member 2 Literature-origin 2(2/0) IEA
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled Literature-origin 1(1/0) TAS[9351641]
CXCL2 chemokine (C-X-C motif) ligand 2 Literature-origin 1(1/0) IBA
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) Literature-origin 1(1/0) IEA
AREG amphiregulin Literature-origin 1(1/0) IDA[12743035]
GPR125 G protein-coupled receptor 125 Literature-origin 1(1/0) IEA
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 Literature-origin 1(1/0) ISS
SSTR5 somatostatin receptor 5 Literature-origin 1(1/0) TAS[9892014]
SORT1 sortilin 1 Literature-origin; Protein mapped 1(1/0) IMP[18258592]
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) Literature-origin 2(2/0) TAS[9144577]
APOE apolipoprotein E Literature-origin; Protein mapped 2(0/2) IDA[16443932]
RGS7BP regulator of G-protein signaling 7 binding protein Literature-origin 1(1/0) IEA
EDN1 endothelin 1 Literature-origin 1(1/0) IDA[17078114]
GPR56 G protein-coupled receptor 56 Literature-origin 1(1/0) IEA
GRM1 glutamate receptor, metabotropic 1 Literature-origin 2(2/0) IDA[24603153]
CCR6 chemokine (C-C motif) receptor 6 Literature-origin 1(1/0) IEA
CCL24 chemokine (C-C motif) ligand 24 Literature-origin 1(1/0) IBA
CCL20 chemokine (C-C motif) ligand 20 Literature-origin 1(1/0) IBA
RGS18 regulator of G-protein signaling 18 Literature-origin 1(1/0) IEA
PTH1R parathyroid hormone 1 receptor Literature-origin 1(1/0) TAS[9745456]
CALM1 calmodulin 1 (phosphorylase kinase, delta) Literature-origin 1(1/0) TAS[10899953]
OXTR oxytocin receptor Literature-origin 1(1/0) IEA
GPR50 G protein-coupled receptor 50 Literature-origin 1(1/0) IEA
NMUR1 neuromedin U receptor 1 Literature-origin 1(1/0) TAS[9782091]