MK4MDD

Gene Report

Basic Information
Approved Symbol KCNK2
Approved Name potassium channel, subfamily K, member 2
Symbol Alias K2p2.1, TREK-1
Location 1q41
Position chr1:215408489-215410436 (+)
External Links Entrez Gene: 3776
Ensembl: ENSG00000082482
UCSC: uc001hkr.4
HGNC ID: 6277
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between KCNK2 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
KCNK2 Liou, 2009 patients and normal controls The genotype frequency of rs6686529 in this gene differed si...... The genotype frequency of rs6686529 in this gene differed significantly between the MDD patients and controls (uncorrected P = 0.00052) and remained statistically significant after correction for multiple comparisons. More...

Positive relationships between KCNK2 and other components at different levels (count: 5) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of KCNK2 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between KCNK2 and MDD (count: 0)
Negative relationships between KCNK2 and other components at different levels (count: 0) Help
KCNK2 related SNPs in MK4MDD (count: 0)
KCNK2 related proteins in MK4MDD (count: 0)
KCNK2 related GO terms (count: 28)
KCNK2 related KEGG pathways (count: 0)
KCNK2 related BioCarta pathways (count: 0)
KCNK2 related Reactome pathways (count: 0)
KCNK2 related interactors from protein-protein interaction data in HPRD (count: 0)