MK4MDD

Gene Report

Basic Information
Approved Symbol ENPP2
Approved Name ectonucleotide pyrophosphatase/phosphodiesterase 2
Previous Symbol PDNP2
Symbol Alias ATX, PD-IALPHA
Name Alias "autotaxin"
Location 8q24.1
Position chr8:120685513-120685644 (-)
External Links Entrez Gene: 5168
Ensembl: ENSG00000136960
UCSC: uc003yos.2
HGNC ID: 3357
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between ENPP2 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
ENPP2 Aston, 2005 patients and normal controls Genes altered in major depressive disorder Genes altered in major depressive disorder
ENPP2 Sibille E, 2009 animal model; patients and nomal controls R=0.88, P-value<5E-6; y slope=1.14 Downregulated in MDD patients Downregulated in MDD patients

Positive relationships between ENPP2 and other components at different levels (count: 0) Help
Positive relationship network of ENPP2 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between ENPP2 and MDD (count: 0)
Negative relationships between ENPP2 and other components at different levels (count: 0) Help
ENPP2 related SNPs in MK4MDD (count: 0)
ENPP2 related proteins in MK4MDD (count: 0)
ENPP2 related GO terms (count: 28)
ENPP2 related KEGG pathways (count: 1)
ENPP2 related BioCarta pathways (count: 0)
ENPP2 related Reactome pathways (count: 0)
ENPP2 related interactors from protein-protein interaction data in HPRD (count: 0)