MK4MDD

Gene Report

Basic Information
Approved Symbol SST
Approved Name somatostatin
Symbol Alias SMST
Name Alias "somatostatin-14", "somatostatin-28", "prepro-somatostatin"
Location 3q28
Position chr3:187388080-187388201 (-)
External Links Entrez Gene: 6750
Ensembl: ENSG00000157005
UCSC: uc003frn.3
HGNC ID: 11329
No. of Studies (Positive/Negative) 3(3/0) Help
Type Literature-origin; Protein mapped

Positive relationships between SST and MDD (count: 3)
Name in Literature Reference Research Type Statistical Result Relation Description Help
neuropeptide somatostatin (SST) Sibille, 2011 patients and normal controls MDD subjects demonstrated reduced SST mRNA expression in th...... MDD subjects demonstrated reduced SST mRNA expression in the dorsolateral prefrontal cortex. More...
SST Guilloux JP, 2012 patients and normal controls genes significantly affected in female MDD subjects genes significantly affected in female MDD subjects
SST Tomita H, 2013 patients and normal controls GPLS genes significantly dysregulated in anterior cingulate ...... GPLS genes significantly dysregulated in anterior cingulate cortex by microarray More...

Positive relationships between SST and other components at different levels (count: 0) Help
Positive relationship network of SST in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between SST and MDD (count: 0)
Negative relationships between SST and other components at different levels (count: 0) Help
SST related SNPs in MK4MDD (count: 0)
SST related proteins in MK4MDD (count: 1)
SST related GO terms (count: 19)
SST related KEGG pathways (count: 0)
SST related BioCarta pathways (count: 0)
SST related Reactome pathways (count: 5)
SST related interactors from protein-protein interaction data in HPRD (count: 5)