MK4MDD

Gene Report

Basic Information
Approved Symbol APOE
Approved Name apolipoprotein E
Previous Symbol AD2
Previous Name "Alzheimer disease 2 (APOE*E4-associated, late onset)"
Location 19q13.31
Position chr19:45412508-45412650 (+)
External Links Entrez Gene: 348
Ensembl: ENSG00000130203
UCSC: uc002pab.3
HGNC ID: 613
No. of Studies (Positive/Negative) 2(0/2) Help
Type Literature-origin; Protein mapped

Positive relationships between APOE and MDD (count: 0)
Positive relationships between APOE and other components at different levels (count: 0) Help
Positive relationship network of APOE in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between APOE and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description
APOE Steffens DC, 2003 nomal people There was no overall association between APOE and depression...... There was no overall association between APOE and depression. More...
APOE Surtees PG, 2009 nomal people No associations were found between APOE genotypes and measu...... No associations were found between APOE genotypes and measures either of past-year or lifetime MDD More...

Negative relationships between APOE and other components at different levels (count: 0) Help
APOE related SNPs in MK4MDD (count: 0)
APOE related proteins in MK4MDD (count: 1)
APOE related GO terms (count: 126)
APOE related KEGG pathways (count: 1)
APOE related BioCarta pathways (count: 0)
APOE related Reactome pathways (count: 3)
APOE related interactors from protein-protein interaction data in HPRD (count: 17)