MK4MDD

Gene Report

Basic Information
Approved Symbol DRD4
Approved Name dopamine receptor D4
Location 11p15.5
Position chr11:640604-640706 (+)
External Links Entrez Gene: 1815
Ensembl: ENSG00000069696
UCSC: uc001lqp.2
HGNC ID: 3025
No. of Studies (Positive/Negative) 2(0/2) Help
Type Literature-origin

Positive relationships between DRD4 and MDD (count: 0)
Positive relationships between DRD4 and other components at different levels (count: 0) Help
Positive relationship network of DRD4 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between DRD4 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description
DRD4 Serretti A, 2001 Patients and nomal controls DRD4 allele and genotype frequencies in bipolars, schizophre...... DRD4 allele and genotype frequencies in bipolars, schizophrenics, delusionals, and psychotic NOS were not significantly different from controls; major depressives showed a trend toward an excess of DRD4*Short and DRD4*Short/Short variants versus controls. More...
DRD4 Aguirre AJ, 2007 Patients and nomal controls There were no differences in allele or genotype frequencies...... There were no differences in allele or genotype frequencies between groups for the 12 bp-VNTR polymorphisms More...

Negative relationships between DRD4 and other components at different levels (count: 0) Help
DRD4 related SNPs in MK4MDD (count: 0)
DRD4 related proteins in MK4MDD (count: 0)
DRD4 related GO terms (count: 52)
DRD4 related KEGG pathways (count: 1)
DRD4 related BioCarta pathways (count: 0)
DRD4 related Reactome pathways (count: 5)
DRD4 related interactors from protein-protein interaction data in HPRD (count: 6)