MK4MDD

SNP Report

Basic Information
Name rs2271933 dbSNP Ensembl
Location Chrchr1:32092525(Forward)
Variant Alleles A/G
Ancestral Allele G
Annotation downstream_gene_variant; intron_variant; missense_variant; nc_transcript_variant
PolyPhen: benign(ENST00000373706, ENST00000403528)
SIFT: tolerated(ENST00000373706, ENST00000403528)
Consequence to Transcript downstream_gene_variant(ENST00000373703, ENST00000461006, ENST00000478502, ENST00000485464, ENST00000489164)
intron_variant(ENST00000373705, ENST00000468521)
missense_variant(ENST00000373706, ENST00000403528)
nc_transcript_variant(ENST00000468521)
No. of Studies (Positive/Negative) 1 (1/0) Help

Positive relationship between rs2271933 and MDD (count: 1)
Reference Research Type Statistical Result Relation Description Help
Rainero I, 2011 Patients and nomal controls p=0.003;OR:1.60; 95% C.I. 1.22-2.10 We found that allelic and genotypic frequencies of the rs22...... We found that allelic and genotypic frequencies of the rs2271933 G>A polymorphism (Ile408Val) in the HCRTR1 gene were significantly different between cases and controls (p=0.003 and p=0.0004, respectively). The carriage of the A allele was associated with a significantly increased disease risk (OR:1.60, 95% C.I. 1.22-2.10). More...

Relationships between rs2271933 and other components at different levels (count: 0) Help
Positive relationship network of rs2271933 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between rs2271933 and MDD (count: 0)
Negative relationships between rs2271933 and other components at different levels (count: 0) Help
rs2271933 related genes (count: 2)