MK4MDD

Gene Report

Basic Information
Approved Symbol GRIA3
Approved Name glutamate receptor, ionotropic, AMPA 3
Previous Symbol GLUR3
Previous Name "glutamate receptor, ionotrophic, AMPA 3"
Symbol Alias GluA3, GLURC, MRX94
Location Xq25
Position chrX:122622564-122624766 (+)
External Links Entrez Gene: 2892
Ensembl: ENSG00000125675
UCSC: uc004etr.4
HGNC ID: 4573
No. of Studies (Positive/Negative) 3(2/1) Help
Type Literature-origin; Protein mapped

Positive relationships between GRIA3 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
GRIA3 Klempan, 2009 patients and normal controls Selected differentially expressed genes in BA44 to BA47 (ANO...... Selected differentially expressed genes in BA44 to BA47 (ANOVA and t-test P < 0.01, fold change 1.3t) More...
GLUR3 Duric V, 2012 patients and normal controls Our findings demonstrate significant dysregulation of synapt...... Our findings demonstrate significant dysregulation of synaptic function/structure related genes SNAP25, DLG2 (SAP93), and MAP1A, and 2-amino-3-(5-methyl-3-oxo-1,2-oxazol-4-yl)propanoic acid receptor subunit genes GLUR1 and GLUR3 More...

Positive relationships between GRIA3 and other components at different levels (count: 0) Help
Positive relationship network of GRIA3 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between GRIA3 and MDD (count: 0)
Negative relationships between GRIA3 and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


GRIA3 related SNPs in MK4MDD (count: 0)
GRIA3 related proteins in MK4MDD (count: 1)
GRIA3 related GO terms (count: 21)
GRIA3 related KEGG pathways (count: 2)
GRIA3 related BioCarta pathways (count: 0)
GRIA3 related Reactome pathways (count: 5)
GRIA3 related interactors from protein-protein interaction data in HPRD (count: 9)