MK4MDD

Gene Report

Basic Information
Approved Symbol GABRB2
Approved Name gamma-aminobutyric acid (GABA) A receptor, beta 2
Name Alias "GABA(A) receptor, beta 2"
Location 5q34
Position chr5:160975065-160975130 (-)
External Links Entrez Gene: 2561
Ensembl: ENSG00000145864
UCSC: uc003lys.1
HGNC ID: 4082
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between GABRB2 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
GABRB2 Aston, 2005 patients and normal controls Genes altered in major depressive disorder Genes altered in major depressive disorder
GABA(A) receptor beta 2 (GABRB2) Zhao J, 2012 patients only We found the transcript levels of GABA(A) receptor beta 2 (G...... We found the transcript levels of GABA(A) receptor beta 2 (GABRB2) and post-synaptic density-95 (PSD-95) to be significantly decreased in the ACC in mood disorder. More...

Positive relationships between GABRB2 and other components at different levels (count: 0) Help
Positive relationship network of GABRB2 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between GABRB2 and MDD (count: 0)
Negative relationships between GABRB2 and other components at different levels (count: 0) Help
GABRB2 related SNPs in MK4MDD (count: 0)
GABRB2 related proteins in MK4MDD (count: 0)
GABRB2 related GO terms (count: 24)
GABRB2 related KEGG pathways (count: 1)
GABRB2 related BioCarta pathways (count: 0)
GABRB2 related Reactome pathways (count: 0)
GABRB2 related interactors from protein-protein interaction data in HPRD (count: 4)