Gene Report

Basic Information

Approved Symbol	GABRG1
Approved Name	gamma-aminobutyric acid (GABA) A receptor, gamma 1
Name Alias	"GABA(A) receptor, gamma"
Location	4p12
Position	chr4:46125931-46126082 (-)
External Links	Entrez Gene: 2565 Ensembl: ENSG00000163285 UCSC: uc003gxb.3 HGNC ID: 4086
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between GABRG1 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
GABRG1	Klempan, 2009	patients and normal controls		Selected differentially expressed genes in BA44 to BA47 (ANO...... Selected differentially expressed genes in BA44 to BA47 (ANOVA and t-test P < 0.01, fold change 1.3t) More...

Positive relationships between GABRG1 and other components at different levels (count: 0)

Positive relationship network of GABRG1 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between GABRG1 and MDD (count: 0)

Negative relationships between GABRG1 and other components at different levels (count: 0)

GABRG1 related SNPs in MK4MDD (count: 0)

GABRG1 related proteins in MK4MDD (count: 0)

GABRG1 related GO terms (count: 11)

ID	Name	Type	Evidence
Literature-origin GO terms
GO:0007268	synaptic transmission	biological process	IEA
GO:0045211	postsynaptic membrane	cellular component	IEA
GO:0030054	cell junction	cellular component	IEA

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0034707	chloride channel complex	cellular component	IEA
GO:0007214	gamma-aminobutyric acid signaling pathway	biological process	IEA
GO:0050811	GABA receptor binding	molecular function	IEA
GO:0004890	GABA-A receptor activity	molecular function	IBA
GO:0005254	chloride channel activity	molecular function	IEA
GO:1902711	GABA-A receptor complex	cellular component	IBA
GO:1902476	chloride transmembrane transport	biological process	IEA
GO:0005230	extracellular ligand-gated ion channel activity	molecular function	IEA

GABRG1 related KEGG pathways (count: 1)

Gene mapped KEGG pathways
ID	Name	Brief Description	Full Description
hsa04080	neuroactive ligand_receptor_interaction	Neuroactive ligand-receptor interaction

GABRG1 related BioCarta pathways (count: 0)

GABRG1 related Reactome pathways (count: 0)

GABRG1 related interactors from protein-protein interaction data in HPRD (count: 1)

Gene Report

Literature-origin GO terms

Gene mapped GO terms

Gene mapped KEGG pathways