MK4MDD

Gene Report

Basic Information
Approved Symbol HADHA
Approved Name hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
Previous Name "hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit"
Symbol Alias GBP, LCEH, LCHAD, MTPA
Name Alias "gastrin-binding protein", "long-chain-3-hydroxyacyl-CoA dehydrogenase", "long-chain 2-enoyl-CoA hydratase", "mitochondrial trifunctional protein, alpha subunit"
Location 2p23
Position chr2:26467465-26467594 (-)
External Links Entrez Gene: 3030
Ensembl: ENSG00000084754
UCSC: uc002rgy.3
HGNC ID: 4801
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between HADHA and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
HADHA Sequeira A, 2009 patients and nomal controls Group: P-value=0.001, F=11.6; Substance: P-value=0.006, F=10.4 Genes differentially expressed after an ANCOVA analysis betw...... Genes differentially expressed after an ANCOVA analysis between the three groups(C = control, S = suicide, SMD = suicide with major depression). More...

Positive relationships between HADHA and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of HADHA in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between HADHA and MDD (count: 0)
Negative relationships between HADHA and other components at different levels (count: 0) Help
HADHA related SNPs in MK4MDD (count: 0)
HADHA related proteins in MK4MDD (count: 0)
HADHA related GO terms (count: 21)
HADHA related KEGG pathways (count: 9)
HADHA related BioCarta pathways (count: 0)
HADHA related Reactome pathways (count: 2)
HADHA related interactors from protein-protein interaction data in HPRD (count: 0)