MK4MDD

Gene Report

Basic Information
Approved Symbol PTK2B
Approved Name protein tyrosine kinase 2 beta
Previous Symbol FAK2
Previous Name "protein tyrosine kinase 2 beta", "PTK2B protein tyrosine kinase 2 beta"
Symbol Alias CAKB, PYK2, RAFTK, PTK, CADTK
Location 8p21.1
Position chr8:27316027-27316904 (+)
External Links Entrez Gene: 2185
Ensembl: ENSG00000120899
UCSC: uc003xfp.2
HGNC ID: 9612
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between PTK2B and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
PTK2B Aston, 2005 patients and normal controls Genes altered in major depressive disorder Genes altered in major depressive disorder
PTK2B Klempan, 2009 patients and normal controls Selected differentially expressed genes in BA44 to BA47 (ANO...... Selected differentially expressed genes in BA44 to BA47 (ANOVA and t-test P < 0.01, fold change 1.3t) More...

Positive relationships between PTK2B and other components at different levels (count: 0) Help
Positive relationship network of PTK2B in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between PTK2B and MDD (count: 0)
Negative relationships between PTK2B and other components at different levels (count: 0) Help
PTK2B related SNPs in MK4MDD (count: 0)
PTK2B related proteins in MK4MDD (count: 0)
PTK2B related GO terms (count: 124)
PTK2B related KEGG pathways (count: 5)
PTK2B related BioCarta pathways (count: 10)
PTK2B related Reactome pathways (count: 0)
PTK2B related interactors from protein-protein interaction data in HPRD (count: 68)