MK4MDD

Gene Report

Basic Information
Approved Symbol FGFR2
Approved Name fibroblast growth factor receptor 2
Previous Symbol KGFR, BEK, CFD1, JWS
Previous Name "bacteria-expressed kinase", "keratinocyte growth factor receptor", "craniofacial dysostosis 1", "Jackson-Weiss syndrome"
Symbol Alias CEK3, TK14, TK25, ECT1, K-SAM, CD332
Name Alias "Crouzon syndrome", "Pfeiffer syndrome"
Location 10q25.3-q26
Position chr10:123357476-123357972 (-)
External Links Entrez Gene: 2263
Ensembl: ENSG00000066468
UCSC: uc021pzy.1
HGNC ID: 3689
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between FGFR2 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
FGFR2 Aston, 2005 patients and normal controls Genes altered in major depressive disorder Genes altered in major depressive disorder
FGFR 2 Evans, 2004 patients and normal controls Of the 10 FGF transcripts reliably detected, 4 were signific...... Of the 10 FGF transcripts reliably detected, 4 were significantly differentially expressed in the DLPFC of MDD subjects, including 2 FGF receptors (FGFR 2 and 3) and 2 FGF ligands (FGF 1 and 9) More...

Positive relationships between FGFR2 and other components at different levels (count: 0) Help
Positive relationship network of FGFR2 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between FGFR2 and MDD (count: 0)
Negative relationships between FGFR2 and other components at different levels (count: 0) Help
FGFR2 related SNPs in MK4MDD (count: 0)
FGFR2 related proteins in MK4MDD (count: 0)
FGFR2 related GO terms (count: 141)
FGFR2 related KEGG pathways (count: 5)
FGFR2 related BioCarta pathways (count: 0)
FGFR2 related Reactome pathways (count: 6)
FGFR2 related interactors from protein-protein interaction data in HPRD (count: 18)