Gene Ontology Report

Basic Information
ID GO:0007165
Name signal transduction
Type biological process

GO:0007165 related genes in MK4MDD (count: 121)
Approved Symbol Approved Name Type No. of Studies (Positive/Negative) Evidence
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Literature-origin; Protein mapped 8(8/0) TAS[7769088]
EBP emopamil binding protein (sterol isomerase) Literature-origin 1(1/0) TAS[7706302]
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 Literature-origin 1(1/0) TAS[8875942|8994832]
NPC1 Niemann-Pick disease, type C1 Literature-origin 1(1/0) IEA; TAS[10521290]
ANK3 ankyrin 3, node of Ranvier (ankyrin G) Literature-origin 1(0/1) IEA
MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) Literature-origin 2(2/0) TAS[9389754]
PTK2B protein tyrosine kinase 2 beta Literature-origin 2(2/0) TAS[7499242|10867021]
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) Literature-origin 1(1/0) TAS[9789079]
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) Literature-origin 1(1/0) TAS[9616127]
FGF1 fibroblast growth factor 1 (acidic) Literature-origin 1(1/0) NAS[3778488]
INPP1 inositol polyphosphate-1-phosphatase Literature-origin 1(1/0) TAS[8390685]
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit Literature-origin 1(1/0) TAS[9575201]
ANGPT2 angiopoietin 2 Literature-origin 1(1/0) TAS[10766762]
CREB1 cAMP responsive element binding protein 1 Literature-origin; Protein mapped 12(10/2) TAS
ITPKB inositol-trisphosphate 3-kinase B Literature-origin 1(1/0) TAS[1654894]
CREM cAMP responsive element modulator Literature-origin 1(0/1) TAS[7916662]
CALM2 calmodulin 2 (phosphorylase kinase, delta) Literature-origin 1(1/0) TAS
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor Literature-origin 1(1/0) TAS[10380922]
PDE1B phosphodiesterase 1B, calmodulin-dependent Literature-origin 1(1/0) TAS
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha Literature-origin; Protein mapped 1(1/0) TAS
NRP1 neuropilin 1 Literature-origin 1(1/0) TAS[9288753]
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) Literature-origin 1(0/1) NAS[16130169]
CSNK1D casein kinase 1, delta Literature-origin 1(0/1) TAS[8786104]
EPS8 epidermal growth factor receptor pathway substrate 8 Literature-origin 1(1/0) TAS[8084614]
CSNK2A1 casein kinase 2, alpha 1 polypeptide Literature-origin 1(0/1) TAS[2174700]
PDE1A phosphodiesterase 1A, calmodulin-dependent Literature-origin 2(2/0) TAS
CALM1 calmodulin 1 (phosphorylase kinase, delta) Literature-origin 1(1/0) TAS
PDE11A phosphodiesterase 11A Literature-origin 2(2/0) IEA
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 Literature-origin 1(1/0) IEA
MAPK12 mitogen-activated protein kinase 12 Literature-origin 1(1/0) TAS[8633070]
RALA v-ral simian leukemia viral oncogene homolog A (ras related) Literature-origin 1(1/0) TAS[2550440|10848592]
CCL24 chemokine (C-C motif) ligand 24 Literature-origin 1(1/0) TAS[9104803]
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 Literature-origin 1(1/0) TAS[7684828]
CAPN3 calpain 3, (p94) Literature-origin 1(1/0) TAS[7720071]
ESR1 estrogen receptor 1 Literature-origin 3(3/0) TAS[10749889|10970861]
ADCY3 adenylate cyclase 3 Literature-origin 2(1/1) TAS
IL1B interleukin 1, beta Literature-origin; Protein mapped 4(3/1) TAS[9218611|10786823]
KIF13B kinesin family member 13B Literature-origin 1(1/0) NAS[10859302]
PDE4A phosphodiesterase 4A, cAMP-specific Literature-origin 1(1/0) IEA
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 Literature-origin; Protein mapped 1(1/0) IDA[18802077]
GRIA2 glutamate receptor, ionotropic, AMPA 2 Literature-origin 1(1/0) TAS[8003671]
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) Literature-origin 7(5/2) TAS[7958835]
CCR6 chemokine (C-C motif) receptor 6 Literature-origin 1(1/0) TAS[9186513]
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 Literature-origin 2(2/0) NAS[8648241]; TAS
PDE8A phosphodiesterase 8A Literature-origin 2(2/0) IEA
SORL1 sortilin-related receptor, L(DLR class) A repeats containing Literature-origin 1(1/0) TAS[9157966]
TOLLIP toll interacting protein Literature-origin 1(1/0) IPI[11441107]
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) Literature-origin 1(1/0) IDA[8906617]
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain Literature-origin 1(1/0) TAS[9314565]
NR4A2 nuclear receptor subfamily 4, group A, member 2 Literature-origin 2(2/0) NAS[7877627]
NFAM1 NFAT activating protein with ITAM motif 1 Literature-origin 1(1/0) IDA[12615919]
ADM adrenomedullin Literature-origin 2(2/0) TAS[10822232]
RAP1GAP RAP1 GTPase activating protein Literature-origin 1(1/0) NAS[10476970]
GABRD gamma-aminobutyric acid (GABA) A receptor, delta Literature-origin 1(1/0) TAS[2176788]
MAPK6 mitogen-activated protein kinase 6 Literature-origin 1(1/0) TAS[2032290]
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase Literature-origin 1(1/0) TAS[7784085]
CCL2 chemokine (C-C motif) ligand 2 Literature-origin; Protein mapped 3(2/1) NAS[10770925]
M6PR mannose-6-phosphate receptor (cation dependent) Literature-origin 1(1/0) TAS[10799489]
KLRC3 killer cell lectin-like receptor subfamily C, member 3 Literature-origin 1(1/0) TAS[9683661]
MAPK1 mitogen-activated protein kinase 1 Literature-origin 2(2/0) TAS[1540184]
PTPRM protein tyrosine phosphatase, receptor type, M Literature-origin 1(1/0) IDA[15080886]
CSNK1E casein kinase 1, epsilon Literature-origin 1(0/1) TAS[7797465]
PRKCH protein kinase C, eta Literature-origin 1(1/0) TAS[1986216]
ERBB3 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 Literature-origin 1(1/0) IDA[10572067]
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 Literature-origin 1(1/0) IEA
ADRA2A adrenoceptor alpha 2A Literature-origin; Protein mapped 2(2/0) TAS[2823383|10896916]
GDNF glial cell derived neurotrophic factor Literature-origin; Protein mapped 1(1/0) TAS[7830769]
KLRK1 killer cell lectin-like receptor subfamily K, member 1 Literature-origin 2(2/0) TAS[2007850]
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) Literature-origin 1(1/0) TAS[7512451|10205054]
PDE10A phosphodiesterase 10A Literature-origin 1(1/0) IEA
EGF epidermal growth factor Literature-origin; SNP mapped; Protein mapped 1(0/1) TAS
CLOCK clock circadian regulator Literature-origin 4(0/4) TAS[10198158]
GRIA1 glutamate receptor, ionotropic, AMPA 1 Literature-origin; Protein mapped 1(1/0) TAS[1311100]
FGF2 fibroblast growth factor 2 (basic) Literature-origin 2(2/0) NAS[9712850]
PTPRT protein tyrosine phosphatase, receptor type, T Literature-origin 1(1/0) NAS[16973135]
RSU1 Ras suppressor protein 1 Literature-origin 1(1/0) TAS[1508180]
IL2RB interleukin 2 receptor, beta Literature-origin 1(1/0) TAS[2785715]
THOC1 THO complex 1 Literature-origin 1(1/0) IEA
ADCY8 adenylate cyclase 8 (brain) Literature-origin 2(2/0) TAS
IL15 interleukin 15 Literature-origin 2(2/0) TAS[8178155]
HGS hepatocyte growth factor-regulated tyrosine kinase substrate Literature-origin 1(1/0) TAS[9407053]
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) Literature-origin 1(1/0) TAS[2674130]
RYK receptor-like tyrosine kinase Literature-origin 1(1/0) TAS[8386829]
IGFBP2 insulin-like growth factor binding protein 2, 36kDa Literature-origin 1(1/0) IEA
PENK proenkephalin Literature-origin 1(1/0) TAS[7057924]
ADCY7 adenylate cyclase 7 Literature-origin 2(2/0) TAS
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type Literature-origin; Protein mapped 1(0/1) TAS[8243272]
GREM1 gremlin 1, DAN family BMP antagonist Literature-origin 1(1/0) ISS
CCL7 chemokine (C-C motif) ligand 7 Literature-origin 1(1/0) TAS[10201901|10770925]
LTA lymphotoxin alpha Literature-origin 2(1/1) TAS[6334807]
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta Literature-origin 1(1/0) TAS
AR androgen receptor Literature-origin 3(3/0) TAS[10835690]
CREBBP CREB binding protein Literature-origin 1(0/1) NAS[15261140]
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase Literature-origin 1(0/1) TAS[1649192]
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 Literature-origin 1(1/0) TAS[9659915]
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 Literature-origin 1(1/0) TAS[1321750]
PRKCB protein kinase C, beta Literature-origin; Protein mapped 1(1/0) NAS[3755548]
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 Literature-origin 1(1/0) IEA
KRT17 keratin 17 Literature-origin 1(1/0) IMP[15795121]
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 Literature-origin; Protein mapped 2(2/0) TAS[2465923]
IL13 interleukin 13 Literature-origin; Protein mapped 1(1/0) NAS[10725748]
ATM ataxia telangiectasia mutated Literature-origin 2(2/0) TAS[7792600]
CRHBP corticotropin releasing hormone binding protein Literature-origin; Protein mapped 2(1/1) TAS[7477348]
GAS6 growth arrest-specific 6 Literature-origin 1(1/0) IDA[7854420|18680538]; TAS[16564713]
FGF3 fibroblast growth factor 3 Literature-origin 1(1/0) TAS[2470007]
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast) Literature-origin 1(1/0) TAS[7962207]
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa Literature-origin 1(1/0) TAS
THBD thrombomodulin Literature-origin 1(1/0) IEA
CCL20 chemokine (C-C motif) ligand 20 Literature-origin 1(1/0) TAS[9038201]
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha Literature-origin 1(1/0) TAS
IL8 interleukin 8 Literature-origin; Protein mapped 2(2/0) TAS[10820279]
ARTN artemin Literature-origin 1(1/0) TAS[9883723]
FGF9 fibroblast growth factor 9 Literature-origin 1(1/0) TAS[8575785]
RAP2B RAP2B, member of RAS oncogene family Literature-origin 1(1/0) TAS[2118648]
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) Literature-origin 1(1/0) NAS[1702217]
DLG4 discs, large homolog 4 (Drosophila) Literature-origin; Protein mapped 1(1/0) TAS[10364559]
DGKG diacylglycerol kinase, gamma 90kDa Literature-origin 1(1/0) TAS[8034597]
MAPK14 mitogen-activated protein kinase 14 Literature-origin 1(1/0) TAS[10706854]
NR3C2 nuclear receptor subfamily 3, group C, member 2 Literature-origin; SNP mapped 3(3/0) TAS[3037703]
SH2D2A SH2 domain containing 2A Literature-origin 1(1/0) TAS[9468509]
LITAF lipopolysaccharide-induced TNF factor Literature-origin 1(1/0) IMP[12761501]