MK4MDD

Gene Report

Basic Information
Approved Symbol NR4A2
Approved Name nuclear receptor subfamily 4, group A, member 2
Previous Symbol NURR1
Symbol Alias TINUR, NOT, RNR1, HZF-3
Location 2q22-q23
Position chr2:157189023-157189227 (-)
External Links Entrez Gene: 4929
Ensembl: ENSG00000153234
UCSC: uc002tyz.4
HGNC ID: 7981
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between NR4A2 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
NR4A2 Kerman IA, 2012 patients and normal controls The greatest changes in expression were observed among trans...... The greatest changes in expression were observed among transcriptional regulators, including downregulation in the expression of TOB1, EGR1, and NR4A2 and their downstream targets. More...
NR4A2 Savitz J, 2013 patients and normal controls FC=1.44; P-value=0.0068401

Positive relationships between NR4A2 and other components at different levels (count: 0) Help
Positive relationship network of NR4A2 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between NR4A2 and MDD (count: 0)
Negative relationships between NR4A2 and other components at different levels (count: 0) Help
NR4A2 related SNPs in MK4MDD (count: 0)
NR4A2 related proteins in MK4MDD (count: 0)
NR4A2 related GO terms (count: 45)
NR4A2 related KEGG pathways (count: 0)
NR4A2 related BioCarta pathways (count: 0)
NR4A2 related Reactome pathways (count: 2)
NR4A2 related interactors from protein-protein interaction data in HPRD (count: 7)