MK4MDD

Gene Report

Basic Information
Approved Symbol GDNF
Approved Name glial cell derived neurotrophic factor
Symbol Alias ATF1, ATF2, HFB1-GDNF
Name Alias "astrocyte-derived trophic factor", "glial cell line derived neurotrophic factor", "glial derived neurotrophic factor"
Location 5p13.1-p12
Position chr5:37839609-37839782 (-)
External Links Entrez Gene: 2668
Ensembl: ENSG00000168621
UCSC: uc011cpg.2
HGNC ID: 4232
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin; Protein mapped

Positive relationships between GDNF and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
GDNF Otsuki, 2008 patients and normal controls Reduced expression levels of GDNF, ARTN, and NT-3 mRNAs were...... Reduced expression levels of GDNF, ARTN, and NT-3 mRNAs were found in patients with major depressive disorder in a current depressive state More...

Positive relationships between GDNF and other components at different levels (count: 0) Help
Positive relationship network of GDNF in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between GDNF and MDD (count: 0)
Negative relationships between GDNF and other components at different levels (count: 0) Help
GDNF related SNPs in MK4MDD (count: 0)
GDNF related proteins in MK4MDD (count: 1)
GDNF related GO terms (count: 37)
GDNF related KEGG pathways (count: 0)
GDNF related BioCarta pathways (count: 0)
GDNF related Reactome pathways (count: 3)
GDNF related interactors from protein-protein interaction data in HPRD (count: 5)