MK4MDD

Gene Report

Basic Information
Approved Symbol IL15
Approved Name interleukin 15
Symbol Alias IL-15, MGC9721
Location 4q31
Position chr4:142654002-142655140 (+)
External Links Entrez Gene: 3600
Ensembl: ENSG00000164136
UCSC: uc003iis.3
HGNC ID: 5977
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between IL15 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
IL-15 Shelton, 2011 patients and normal controls Gene set analysis suggested up-regulation of a variety of pr...... Gene set analysis suggested up-regulation of a variety of pro- and anti-inflammatory cytokines, including interleukin 1alpha (IL-1alpha), IL-2, IL-3, IL-5, IL-8, IL-9, IL-10, IL-12A, IL-13, IL-15, IL-18, interferon gamma (IFNgamma), and lymphotoxin alpha (TNF superfamily member 1). More...

Positive relationships between IL15 and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of IL15 in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between IL15 and MDD (count: 0)
Negative relationships between IL15 and other components at different levels (count: 0) Help
IL15 related SNPs in MK4MDD (count: 0)
IL15 related proteins in MK4MDD (count: 0)
IL15 related GO terms (count: 39)
IL15 related KEGG pathways (count: 3)
IL15 related BioCarta pathways (count: 2)
IL15 related Reactome pathways (count: 0)
IL15 related interactors from protein-protein interaction data in HPRD (count: 3)