MK4MDD

Gene Report

Basic Information
Approved Symbol ITPR1
Approved Name inositol 1,4,5-trisphosphate receptor, type 1
Previous Symbol SCA15, SCA16, SCA29
Previous Name "spinocerebellar ataxia 15", "spinocerebellar ataxia 16", "spinocerebellar ataxia 29"
Symbol Alias Insp3r1, IP3R1, ACV
Location 3p26.1
Position chr3:4887910-4889186 (+)
External Links Entrez Gene: 3708
Ensembl: ENSG00000150995
UCSC: uc003bqc.3
HGNC ID: 6180
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between ITPR1 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
ITPR1 Sequeira, 2007 patients and normal controls Selected differentially expressed genes in hippocampus Selected differentially expressed genes in hippocampus
ITPR Tomita H, 2013 patients and normal controls GPLS genes significantly dysregulated in anterior cingulate ...... GPLS genes significantly dysregulated in anterior cingulate cortex by microarray More...

Positive relationships between ITPR1 and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of ITPR1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between ITPR1 and MDD (count: 0)
Negative relationships between ITPR1 and other components at different levels (count: 0) Help
ITPR1 related SNPs in MK4MDD (count: 0)
ITPR1 related proteins in MK4MDD (count: 0)
ITPR1 related GO terms (count: 44)
ITPR1 related KEGG pathways (count: 10)
ITPR1 related BioCarta pathways (count: 0)
ITPR1 related Reactome pathways (count: 16)
ITPR1 related interactors from protein-protein interaction data in HPRD (count: 27)