MK4MDD

Gene Report

Basic Information
Approved Symbol ATM
Approved Name ataxia telangiectasia mutated
Previous Symbol ATA, ATDC, ATC, ATD
Previous Name "ataxia telangiectasia mutated (includes complementation groups A, C and D)"
Symbol Alias TEL1, TELO1
Name Alias "TEL1, telomere maintenance 1, homolog (S. cerevisiae)"
Location 11q22-q23
Position chr11:108236236-108239826 (+)
External Links Entrez Gene: 472
Ensembl: ENSG00000149311
UCSC: uc001pkb.1
HGNC ID: 795
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between ATM and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
ATM Aston, 2005 patients and normal controls Genes altered in major depressive disorder Genes altered in major depressive disorder
ATM Jansen R, 2015 patients and normal controls P-value=0.000107;FDR=0.0853;beta=-0.218 we found 129 genes (142 probesets) differentially expressed ...... we found 129 genes (142 probesets) differentially expressed between the control and current MDD groups (FDR<0.1) More...

Positive relationships between ATM and other components at different levels (count: 0) Help
Positive relationship network of ATM in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between ATM and MDD (count: 0)
Negative relationships between ATM and other components at different levels (count: 0) Help
ATM related SNPs in MK4MDD (count: 0)
ATM related proteins in MK4MDD (count: 0)
ATM related GO terms (count: 70)
ATM related KEGG pathways (count: 3)
ATM related BioCarta pathways (count: 8)
ATM related Reactome pathways (count: 6)
ATM related interactors from protein-protein interaction data in HPRD (count: 40)