
Gene Report
Approved Symbol | KAT5 |
---|---|
Approved Name | K(lysine) acetyltransferase 5 |
Previous Symbol | HTATIP |
Previous Name | HIV-1 Tat interactive protein, 60kDa |
Symbol Alias | TIP60, PLIP, cPLA2, HTATIP1, ESA1, ZC2HC5 |
Name Alias | Tat interacting protein, 60kDa, "K-acetyltransferase 5" |
Location | 11q13 |
Position | chr11:65479473-65487077 (+) |
External Links |
Entrez Gene: 10524 Ensembl: ENSG00000172977 UCSC: uc001ofk.3 HGNC ID: 5275 |
No. of Studies (Positive/Negative) | 1(1/0)
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Type | Literature-origin |
Name in Literature | Reference | Research Type | Statistical Result | Relation Description | ![]() |
---|---|---|---|---|---|
Cytosolic phospholipase A2 (cPLA2) | Pae, 2004 | patients and normal controls | P-value = 0.007, odds ratio = 1.827; confidence interval = 1.141-2.927 | Genotype and allele distributions in MDD patients were signi...... Genotype and allele distributions in MDD patients were significantly different from those of the controls. In particular, the A2 allele was associated with increased risk of MDD development (p = 0.007, odds ratio = 1.827; confidence interval = 1.141-2.927) More... |
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus | Protein and Other Molecule | Cell and Molecular Pathway | Neural System | Cognition and Behavior | Symptoms and Signs | Environment | MDD |
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2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Approved Name | UniportKB | No. of Studies (Positive/Negative) | Source | |
---|---|---|---|---|
Histone acetyltransferase KAT5 | Q92993 | 0(0/0) | Gene mapped |
Gene mapped GO terms | ||||
ID | Name | Type | Evidence | |
---|---|---|---|---|
GO:0005634 | nucleus | cellular component | IDA | |
GO:0032703 | negative regulation of interleukin-2 production | biological process | IDA[17360565] | |
GO:0045893 | positive regulation of transcription, DNA-dependent | biological process | IDA[14966270]; NAS[15572661] | |
GO:0050681 | androgen receptor binding | molecular function | NAS[15572661] | |
GO:0035267 | NuA4 histone acetyltransferase complex | cellular component | IDA[14966270] | |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | biological process | IEA | |
GO:0006351 | transcription, DNA-dependent | biological process | IEA | |
GO:0048471 | perinuclear region of cytoplasm | cellular component | IEA | |
GO:0006978 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | biological process | IDA[14966270] | |
GO:0000122 | negative regulation of transcription from RNA polymerase II promoter | biological process | IMP[17360565] | |
GO:0005829 | cytosol | cellular component | IEA | |
GO:0040008 | regulation of growth | biological process | IEA | |
GO:0070491 | repressing transcription factor binding | molecular function | IPI[17360565] | |
GO:0046872 | metal ion binding | molecular function | IEA | |
GO:0016573 | histone acetylation | biological process | IDA[10966108] | |
GO:0005515 | protein binding | molecular function | IPI | |
GO:0032777 | Piccolo NuA4 histone acetyltransferase complex | cellular component | IDA[14966270] | |
GO:0045892 | negative regulation of transcription, DNA-dependent | biological process | IDA[17360565] | |
GO:0004402 | histone acetyltransferase activity | molecular function | IDA[14966270] | |
GO:0000785 | chromatin | cellular component | IEA | |
GO:0030521 | androgen receptor signaling pathway | biological process | NAS[15572661] | |
GO:0006302 | double-strand break repair | biological process | IMP[10966108] | |
GO:0019048 | virus-host interaction | biological process | IEA | |
GO:0003713 | transcription coactivator activity | molecular function | IDA[14966270]; TAS[17360565] | |
GO:0005667 | transcription factor complex | cellular component | IEA | |
GO:0005730 | nucleolus | cellular component | IDA[16387653]; IDA | |
GO:0032403 | protein complex binding | molecular function | IEA |

Gene | Interactor | Interactor in MK4MDD? | Experiment Type | PMID | |
---|---|---|---|---|---|
KAT5 | GEMIN7 | No | yeast 2-hybrid | 16169070 | |
KAT5 | CCNB1 | No | in vitro;in vivo | 12468530 | |
KAT5 | TELO2 | No | yeast 2-hybrid | 16169070 | |
KAT5 | E2F1 | No | in vitro | 15121871 | |
KAT5 | HNRNPH3 | No | yeast 2-hybrid | 16169070 | |
KAT5 | ZEB1 | No | yeast 2-hybrid | 11275565 | |
KAT5 | PLEKHA4 | No | yeast 2-hybrid | 16169070 | |
KAT5 | ESR1 | Yes | in vitro;in vivo | 16260778 | |
KAT5 | SYN1 | Yes | yeast 2-hybrid | 16169070 | |
KAT5 | PITX2 | No | in vivo | 12464179 | |
KAT5 | CDK5RAP2 | No | yeast 2-hybrid | 16169070 | |
KAT5 | ETV6 | No | in vitro;in vivo;yeast 2-hybrid | 12737628 | |
KAT5 | MYC | No | in vitro;in vivo | 12776177 , 15572685 | |
KAT5 | MAD2L1BP | No | yeast 2-hybrid | 16169070 | |
KAT5 | NDUFV2 | No | yeast 2-hybrid | 16169070 | |
KAT5 | APP | No | in vivo | 12032152 | |
KAT5 | ATM | Yes | in vitro;in vivo | 16141325 | |
KAT5 | DLEU1 | No | in vitro;yeast 2-hybrid | 16169070 | |
KAT5 | HABP4 | No | yeast 2-hybrid | 16455055 | |
KAT5 | HIST2H2AC | No | in vitro | 10096020 | |
KAT5 | LMNA | No | in vitro;yeast 2-hybrid | 16169070 | |
KAT5 | HDAC1 | No | in vivo | 11994312 | |
KAT5 | CREB1 | Yes | in vitro;in vivo | 10720489 | |
KAT5 | EFNA1 | No | yeast 2-hybrid | 16169070 | |
KAT5 | POLE2 | No | in vitro;yeast 2-hybrid | 16169070 | |
KAT5 | CSTF2 | No | yeast 2-hybrid | 16169070 | |
KAT5 | TRIB3 | No | in vitro;yeast 2-hybrid | 16169070 | |
KAT5 | CREBBP | Yes | in vivo | 16001085 | |
KAT5 | BCL3 | No | in vitro;in vivo;yeast 2-hybrid | 10362352 , 15829968 | |
KAT5 | GSTO1 | No | yeast 2-hybrid | 16169070 | |
KAT5 | ALOX12 | No | in vivo | 15474031 | |
KAT5 | EDNRA | No | in vitro;in vivo;yeast 2-hybrid | 11262386 | |
KAT5 | NDUFA4L2 | No | yeast 2-hybrid | 16169070 | |
KAT5 | C1orf174 | No | yeast 2-hybrid | 16169070 | |
KAT5 | IL9R | No | in vivo;yeast 2-hybrid | 10486269 | |
KAT5 | C7orf20 | No | yeast 2-hybrid | 16169070 | |
KAT5 | ARIH2 | No | yeast 2-hybrid | 16169070 | |
KAT5 | ATXN1 | No | in vitro;in vivo | 17110330 | |
KAT5 | EP300 | Yes | in vivo | 16001085 | |
KAT5 | BARD1 | No | yeast 2-hybrid | 15383276 | |
KAT5 | PLA2G4A | No | in vivo;yeast 2-hybrid | 11416127 | |
KAT5 | CDK1 | No | in vitro;in vivo | 12468530 | |
KAT5 | NFKB1 | No | in vivo | 15829968 | |
KAT5 | POLR3F | No | in vitro;yeast 2-hybrid | 16169070 | |
KAT5 | PTPN4 | No | in vitro;yeast 2-hybrid | 16169070 | |
KAT5 | LRP1 | No | in vitro;in vivo | 12888553 | |
KAT5 | AR | Yes | in vitro;in vivo;yeast 2-hybrid | 11994312 , 10364196 | |
KAT5 | FAM101B | No | yeast 2-hybrid | 16169070 | |
KAT5 | BMI1 | No | yeast 2-hybrid | 16169070 | |
KAT5 | GAPDH | No | yeast 2-hybrid | 15383276 | |
KAT5 | PTPRS | No | in vitro;yeast 2-hybrid | 16169070 | |
KAT5 | TP53 | No | in vivo | 16601686 | |
KAT5 | HAP1 | No | in vitro;yeast 2-hybrid | 15383276 | |
KAT5 | HDAC7 | No | in vivo | 12551922 | |
KAT5 | FAM135B | No | yeast 2-hybrid | 16169070 | |
KAT5 | PDCD5 | No | yeast 2-hybrid | 16169070 | |
KAT5 | KIAA1377 | No | in vitro;yeast 2-hybrid | 15383276 | |
KAT5 | CDC42 | No | yeast 2-hybrid | 16169070 | |
KAT5 | MDM2 | No | in vitro;in vivo | 11927554 | |
KAT5 | H3F3B | No | in vitro | 10096020 | |
KAT5 | APBB1 | No | in vitro;yeast 2-hybrid | 11441186 | |
KAT5 | SAT1 | Yes | yeast 2-hybrid | 16169070 | |
KAT5 | ZNF24 | No | in vitro;yeast 2-hybrid | 16169070 | |
KAT5 | SNRPD2 | No | yeast 2-hybrid | 16169070 | |
KAT5 | OGFOD2 | No | yeast 2-hybrid | 16169070 | |
KAT5 | GADD45G | No | in vitro;yeast 2-hybrid | 15383276 | |
KAT5 | NAP1L5 | No | yeast 2-hybrid | 16169070 , 16189514 | |
KAT5 | SNAPIN | No | yeast 2-hybrid | 16169070 | |
KAT5 | FAM173A | No | yeast 2-hybrid | 16169070 | |
KAT5 | HIST2H4A | No | in vitro | 10096020 | |
KAT5 | CRELD1 | No | yeast 2-hybrid | 16169070 | |
KAT5 | CBX8 | No | yeast 2-hybrid | 16169070 | |
KAT5 | RGL2 | No | yeast 2-hybrid | 16169070 | |
KAT5 | STAT3 | No | in vivo | 12551922 | |
KAT5 | CCT7 | No | yeast 2-hybrid | 16169070 | |
KAT5 | CCDC106 | No | yeast 2-hybrid | 16169070 | |
KAT5 | IK | No | in vitro;yeast 2-hybrid | 16169070 |