MK4MDD

Gene Report

Basic Information
Approved Symbol SYN1
Approved Name synapsin I
Location Xp11.2
Position chrX:47479128-47479256 (-)
External Links Entrez Gene: 6853
Ensembl: ENSG00000008056
UCSC: uc004die.3
HGNC ID: 11494
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin; Protein mapped

Positive relationships between SYN1 and MDD (count: 3)
Name in Literature Reference Research Type Statistical Result Relation Description Help
SYN1 Kang HJ, 2012 patients and normal controls Here we use microarray gene profiling and electron microscop...... Here we use microarray gene profiling and electron microscopic stereology to reveal lower expression of synaptic-function-related genes (CALM2, SYN1, RAB3A, RAB4B and TUBB4) in the dlPFC of subjects with MDD and a corresponding lower number of synapses. We also identify a transcriptional repressor, GATA1, expression of which is higher in MDD More...
SYN1a Cruceanu C, 2013 patients and normal controls FC=2.20; P-value<0.01
SYN1b Cruceanu C, 2013 patients and normal controls FC=1.76; P-value<0.05

Positive relationships between SYN1 and other components at different levels (count: 0) Help
Positive relationship network of SYN1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between SYN1 and MDD (count: 0)
Negative relationships between SYN1 and other components at different levels (count: 0) Help
SYN1 related SNPs in MK4MDD (count: 0)
SYN1 related proteins in MK4MDD (count: 1)
SYN1 related GO terms (count: 21)
SYN1 related KEGG pathways (count: 0)
SYN1 related BioCarta pathways (count: 0)
SYN1 related Reactome pathways (count: 4)
SYN1 related interactors from protein-protein interaction data in HPRD (count: 26)