Gene Report
Approved Symbol | SAT1 |
---|---|
Approved Name | spermidine/spermine N1-acetyltransferase 1 |
Previous Symbol | SAT |
Previous Name | spermidine/spermine N1-acetyltransferase |
Symbol Alias | SSAT |
Name Alias | diamine N-acetyltransferase 1 |
Location | Xp22.1 |
Position | chrX:23801275-23804327 (+) |
External Links |
Entrez Gene: 6303 Ensembl: ENSG00000130066 UCSC: uc004dau.3 HGNC ID: 10540 |
No. of Studies (Positive/Negative) | 4(4/0) |
Type | Literature-origin |
Name in Literature | Reference | Research Type | Statistical Result | Relation Description | |
---|---|---|---|---|---|
SSAT | Sequeira, 2007 | patients and normal controls | Selected differentially expressed genes in BA29 Selected differentially expressed genes in BA29 | ||
SAT | Klempan, 2009 | patients and normal controls | Selected differentially expressed genes in BA44 to BA47 (ANO...... Selected differentially expressed genes in BA44 to BA47 (ANOVA and t-test P < 0.01, fold change 1.3t) More... |
Genetic/epigenetic locus | Protein and other molecule | Cell and molecular pathway | Neural system | Cognition and behavior | Symptoms and signs | Environment | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus | Protein and Other Molecule | Cell and Molecular Pathway | Neural System | Cognition and Behavior | Symptoms and Signs | Environment | MDD |
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web
Approved Name | UniportKB | No. of Studies (Positive/Negative) | Source | |
---|---|---|---|---|
Diamine acetyltransferase 1 | P21673 | 0(0/0) | Gene mapped |
Gene mapped GO terms | ||||
ID | Name | Type | Evidence | |
---|---|---|---|---|
GO:0006596 | polyamine biosynthetic process | biological process | TAS | |
GO:0001525 | angiogenesis | biological process | IEP[11866539] | |
GO:0006595 | polyamine metabolic process | biological process | TAS | |
GO:0019809 | spermidine binding | molecular function | IEA | |
GO:0005622 | intracellular | cellular component | IDA | |
GO:0004145 | diamine N-acetyltransferase activity | molecular function | IEA | |
GO:0034641 | cellular nitrogen compound metabolic process | biological process | TAS | |
GO:0044281 | small molecule metabolic process | biological process | TAS | |
GO:0005515 | protein binding | molecular function | IPI[19060904] | |
GO:0005829 | cytosol | cellular component | TAS | |
GO:0009447 | putrescine catabolic process | biological process | IEA | |
GO:0042127 | regulation of cell proliferation | biological process | IEA |
Gene mapped KEGG pathways | ||||
ID | Name | Brief Description | Full Description | |
---|---|---|---|---|
hsa00330 | arginine and_proline_metabolism | Arginine and proline metabolism |
Gene mapped Reactome pathways | |||
ID | Name | Description | |
---|---|---|---|
REACT_13 | metabolism of_amino_acids | This group of reactions is responsible for: 1) the breakdown...... This group of reactions is responsible for: 1) the breakdown of amino acids; 2) the synthesis of urea from ammonia and amino groups generated by amino acid breakdown; 3) the synthesis of the ten amino acids that are not essential components of the human diet; and 4) the synthesis of related nitrogen-containing molecules including carnitine and creatine. More... |
SAT1 related interactors from protein-protein interaction data in HPRD (count: 54)
Gene | Interactor | Interactor in MK4MDD? | Experiment Type | PMID | |
---|---|---|---|---|---|
SAT1 | SAT1 | Yes | in vivo;yeast 2-hybrid | 8670140 , 16189514 | |
SAT1 | HOXB9 | No | yeast 2-hybrid | 16189514 | |
SAT1 | TP53 | No | yeast 2-hybrid | 16169070 | |
SAT1 | FUNDC2 | No | yeast 2-hybrid | 16169070 | |
SAT1 | DNPEP | No | yeast 2-hybrid | 16189514 | |
SAT1 | UNC119 | No | yeast 2-hybrid | 16169070 | |
SAT1 | TCF25 | No | yeast 2-hybrid | 16189514 | |
SAT1 | ITGB1BP3 | No | yeast 2-hybrid | 16169070 | |
SAT1 | C7orf64 | No | yeast 2-hybrid | 16169070 | |
SAT1 | LUC7L2 | No | yeast 2-hybrid | 16169070 | |
SAT1 | TLE1 | No | yeast 2-hybrid | 16169070 | |
SAT1 | ABCB8 | No | yeast 2-hybrid | 16169070 | |
SAT1 | TACO1 | No | yeast 2-hybrid | 16189514 | |
SAT1 | MYST2 | No | yeast 2-hybrid | 16169070 | |
SAT1 | INO80C | No | yeast 2-hybrid | 16169070 | |
SAT1 | KCNA4 | Yes | yeast 2-hybrid | 16169070 | |
SAT1 | SAT2 | Yes | yeast 2-hybrid | 16189514 | |
SAT1 | COPS6 | No | yeast 2-hybrid | 16169070 | |
SAT1 | FAM86C | No | yeast 2-hybrid | 16189514 | |
SAT1 | CSNK2A1 | No | in vitro | 8954982 | |
SAT1 | GBP2 | No | yeast 2-hybrid | 16169070 | |
SAT1 | UBE2D3 | No | in vitro | 11485561 | |
SAT1 | TP53AP1 | No | yeast 2-hybrid | 16169070 | |
SAT1 | RPLP1 | No | yeast 2-hybrid | 16169070 | |
SAT1 | CSNK2A2 | No | in vitro | 8954982 | |
SAT1 | HOXB6 | No | yeast 2-hybrid | 16189514 | |
SAT1 | FAM176A | No | yeast 2-hybrid | 16169070 | |
SAT1 | UTP14A | No | yeast 2-hybrid | 16169070 | |
SAT1 | C9orf46 | No | yeast 2-hybrid | 16169070 | |
SAT1 | GDF9 | No | yeast 2-hybrid | 16169070 | |
SAT1 | SEPHS1 | No | yeast 2-hybrid | 16169070 | |
SAT1 | RBM17 | No | yeast 2-hybrid | 16189514 | |
SAT1 | APLP1 | Yes | yeast 2-hybrid | 16169070 | |
SAT1 | TMEM66 | No | yeast 2-hybrid | 16169070 | |
SAT1 | B4GALT3 | No | yeast 2-hybrid | 16169070 | |
SAT1 | PTN | Yes | yeast 2-hybrid | 16169070 | |
SAT1 | CRMP1 | No | yeast 2-hybrid | 16169070 | |
SAT1 | TSC22D4 | No | yeast 2-hybrid | 16189514 | |
SAT1 | KAT5 | Yes | yeast 2-hybrid | 16169070 | |
SAT1 | DGKZ | No | yeast 2-hybrid | 16169070 | |
SAT1 | FTSJ3 | No | yeast 2-hybrid | 16189514 | |
SAT1 | CCDC90B | No | yeast 2-hybrid | 16169070 | |
SAT1 | CHD3 | No | yeast 2-hybrid | 16169070 | |
SAT1 | KIAA1377 | No | yeast 2-hybrid | 16169070 | |
SAT1 | C1orf103 | No | yeast 2-hybrid | 16169070 | |
SAT1 | SETDB1 | Yes | yeast 2-hybrid | 16169070 | |
SAT1 | HSPE1 | No | yeast 2-hybrid | 16169070 | |
SAT1 | ITGA9 | No | in vivo;yeast 2-hybrid | 15479742 | |
SAT1 | EEF1G | No | yeast 2-hybrid | 16169070 | |
SAT1 | MED31 | No | yeast 2-hybrid | 16169070 | |
SAT1 | ZHX1 | No | yeast 2-hybrid | 16169070 | |
SAT1 | C14orf1 | No | yeast 2-hybrid | 16169070 | |
SAT1 | LNX1 | No | yeast 2-hybrid | 16189514 | |
SAT1 | EPHB6 | No | yeast 2-hybrid | 16169070 |