Reactome Pathway Report
Basic Information
| ID |
|
| Name |
metabolism of_amino_acids
|
| Description |
This group of reactions is responsible for: 1) the breakdown of amino acids; 2) the synthesis of urea from ammonia and amino groups generated by amino acid breakdown; 3) the synthesis of the ten amino acids that are not essential components of the human diet; and 4) the synthesis of related nitrogen-containing molecules including carnitine and creatine.
|
REACT_13 related genes in MK4MDD (count: 19)
| Approved Symbol |
Approved Name |
Type |
No. of Studies (Positive/Negative) |
| SLC3A2 |
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 |
Protein mapped
|
0(0/0) |
| PSMD11 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
Literature-origin
|
1(1/0) |
| SLC25A21 |
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
SNP mapped
|
0(0/0) |
| SMOX |
spermine oxidase |
Literature-origin
|
1(1/0) |
| GLUL |
glutamate-ammonia ligase |
Literature-origin; Protein mapped
|
3(3/0) |
| AGMAT |
agmatine ureohydrolase (agmatinase) |
Protein mapped
|
0(0/0) |
| KYNU |
kynureninase |
Protein mapped
|
0(0/0) |
| AMD1 |
adenosylmethionine decarboxylase 1 |
Literature-origin
|
1(1/0) |
| KMO |
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
Protein mapped
|
0(0/0) |
| SMS |
spermine synthase |
Literature-origin
|
1(1/0) |
| SLC6A15 |
solute carrier family 6 (neutral amino acid transporter), member 15 |
Literature-origin
|
2(2/0) |
| PSMB4 |
proteasome (prosome, macropain) subunit, beta type, 4 |
Literature-origin
|
1(1/0) |
| GATM |
glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
Literature-origin
|
1(1/0) |
| SLC1A4 |
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
Protein mapped
|
0(0/0) |
| IDO1 |
indoleamine 2,3-dioxygenase 1 |
Protein mapped
|
0(0/0) |
| SAT1 |
spermidine/spermine N1-acetyltransferase 1 |
Literature-origin
|
4(4/0) |
| BCAT1 |
branched chain amino-acid transaminase 1, cytosolic |
Literature-origin
|
1(1/0) |
| GLUD1 |
glutamate dehydrogenase 1 |
Protein mapped
|
0(0/0) |
| NQO1 |
NAD(P)H dehydrogenase, quinone 1 |
Literature-origin
|
1(0/1) |
