MK4MDD

Gene Report

Basic Information
Approved Symbol PSMB4
Approved Name proteasome (prosome, macropain) subunit, beta type, 4
Symbol Alias HN3, PROS26
Location 1q21
Position chr1:151374306-151374412 (+)
External Links Entrez Gene: 5692
Ensembl: ENSG00000159377
UCSC: uc001eyc.1
HGNC ID: 9541
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between PSMB4 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
PSMB4 Wong, 2008 patients and normal controls Specifically, single nucleotide polymorphisms (SNPs) in two ...... Specifically, single nucleotide polymorphisms (SNPs) in two genes critical for T-cell function are associated with susceptibility to MDD: PSMB4 (proteasome beta4 subunit), important for antigen processing, and TBX21 (T bet), critical for differentiation. More...

Positive relationships between PSMB4 and other components at different levels (count: 0) Help
Positive relationship network of PSMB4 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between PSMB4 and MDD (count: 0)
Negative relationships between PSMB4 and other components at different levels (count: 0) Help
PSMB4 related SNPs in MK4MDD (count: 0)
PSMB4 related proteins in MK4MDD (count: 0)
PSMB4 related GO terms (count: 50)
PSMB4 related KEGG pathways (count: 1)
PSMB4 related BioCarta pathways (count: 1)
PSMB4 related Reactome pathways (count: 25)
PSMB4 related interactors from protein-protein interaction data in HPRD (count: 2)