MK4MDD

Gene Report

Basic Information
Approved Symbol SLC6A15
Approved Name solute carrier family 6 (neutral amino acid transporter), member 15
Previous Name "solute carrier family 6 (neurotransmitter transporter), member 15"
Symbol Alias hv7-3, NTT73, FLJ10316, V7-3, SBAT1
Name Alias "homolog of rat orphan transporter v7-3", "sodium/chloride dependent neurotransmitter transporter Homo sapiens orphan neurotransmitter transporter NTT7"
Location 12q21.31
Position chr12:85306302-85306608 (-)
External Links Entrez Gene: 55117
Ensembl: ENSG00000072041
UCSC: uc001szv.4
HGNC ID: 13621
No. of Studies (Positive/Negative) 3(2/1) Help
Type Literature-origin

Positive relationships between SLC6A15 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
SLC6A15 Chu TT, 2009 Patients and nomal controls Down regulation, fold change([MD] vs [C]) 2.1041868 Down regulation, fold change([MD] vs [C]) 2.1041868

Positive relationships between SLC6A15 and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of SLC6A15 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between SLC6A15 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description
SLC6A15 Quast C, 2013 patients and normal controls While none of the non-synonymous coding variants showed sign...... While none of the non-synonymous coding variants showed significant differences in case-control associations More...

Negative relationships between SLC6A15 and other components at different levels (count: 0) Help
SLC6A15 related SNPs in MK4MDD (count: 0)
SLC6A15 related proteins in MK4MDD (count: 0)
SLC6A15 related GO terms (count: 15)
SLC6A15 related KEGG pathways (count: 0)
SLC6A15 related BioCarta pathways (count: 0)
SLC6A15 related Reactome pathways (count: 9)
SLC6A15 related interactors from protein-protein interaction data in HPRD (count: 0)