MK4MDD

Gene Report

Basic Information
Approved Symbol ESR1
Approved Name estrogen receptor 1
Previous Symbol ESR
Symbol Alias NR3A1, Era
Location 6q24-q27
Position chr6:152420102-152420188 (+)
External Links Entrez Gene: 2099
Ensembl: ENSG00000091831
UCSC: uc003qon.4
HGNC ID: 3467
No. of Studies (Positive/Negative) 3(3/0) Help
Type Literature-origin

Positive relationships between ESR1 and MDD (count: 3)
Name in Literature Reference Research Type Statistical Result Relation Description Help
ER-alpha Tsai, 2003 patients and normal controls P-value<0.05 Statistical analysis showed a significant difference in the ...... Statistical analysis showed a significant difference in the II genotype and allele frequencies between the female MDD patients and the female controls ( P=0.010 and P=0.004, respectively). More...
ER Geng, 2007 patients and normal controls AR gene in MDD group have shorter microsatellites' length, a...... AR gene in MDD group have shorter microsatellites' length, and ER beta gene have shorter microsatellites' length and higher rates of S alleles, SS, genotype, and lower rate of LL genotype than control group. More...
ESR1 Ryan J, 2012 nomal people P-value=0.009 Women homozygous for the variant G allele of ESR1 rs9340799 ...... Women homozygous for the variant G allele of ESR1 rs9340799 had a 1.6-fold increased risk of MDD across their lifetime compared with women who were homozygous for the A allele (p=0.009) More...

Positive relationships between ESR1 and other components at different levels (count: 0) Help
Positive relationship network of ESR1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between ESR1 and MDD (count: 0)
Negative relationships between ESR1 and other components at different levels (count: 0) Help
ESR1 related SNPs in MK4MDD (count: 0)
ESR1 related proteins in MK4MDD (count: 0)
ESR1 related GO terms (count: 87)
ESR1 related KEGG pathways (count: 0)
ESR1 related BioCarta pathways (count: 3)
ESR1 related Reactome pathways (count: 2)
ESR1 related interactors from protein-protein interaction data in HPRD (count: 189)