SNP Report

Name	rs9340799 dbSNP Ensembl
Location	Chrchr6:152163381(Forward)
Variant Alleles	A/G
Ancestral Allele	A
Annotation	intron_variant
Consequence to Transcript	intron_variant(ENST00000206249, ENST00000338799, ENST00000406599, ENST00000427531, ENST00000440973, ENST00000443427, ENST00000456483, ENST00000544394)
No. of Studies (Positive/Negative)	2 (2/0)

Reference	Research Type	Statistical Result	Relation Description
Bosker, 2010	patients and normal controls		Significance of candidate SNPs for MDD identified from the l...... Significance of candidate SNPs for MDD identified from the literature within the GAIN MDD GWAS More...
Ryan J, 2012	nomal people	P-value=0.009	Women homozygous for the variant G allele of ESR1 rs9340799 ...... Women homozygous for the variant G allele of ESR1 rs9340799 had a 1.6-fold increased risk of MDD across their lifetime compared with women who were homozygous for the A allele (p=0.009) More...

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Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Approved Symbol	Approved Name	Type	No. of Studies (Positive/Negative)
ESR1	estrogen receptor 1	Literature-origin; SNP mapped	3(3/0)