MK4MDD

Gene Report

Basic Information
Approved Symbol GNAL
Approved Name guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
Location 18p11.22-p11.21
Position chr18:11883968-11885679 (+)
External Links Entrez Gene: 2774
Ensembl: ENSG00000141404
UCSC: uc002kqc.3
HGNC ID: 4388
No. of Studies (Positive/Negative) 1(0/1) Help
Type Literature-origin; Protein mapped

Positive relationships between GNAL and MDD (count: 0)
Positive relationships between GNAL and other components at different levels (count: 0) Help
Positive relationship network of GNAL in MK4MDD
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Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between GNAL and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description
GNAL Zill P, 2002 Patients and nomal controls In the control group, we found a significant increase in the...... In the control group, we found a significant increase in the G-allele frequency of the intron 3 polymorphism in females (P=0.0036, odds ratio=2.13, 95% confidence interval=1.29-3.54, Fisher's Exact Test). In patients, we found a similar tendency for higher G-allele frequencies in females. Concerning the intron 10 polymorphism, no differences in the genotype or allele frequencies were detectable for any of the separated gender groups. Also, the total patient and control groups showed no differences in allele or genotype frequencies for any of the investigated polymorphisms. More...

Negative relationships between GNAL and other components at different levels (count: 0) Help
GNAL related SNPs in MK4MDD (count: 0)
GNAL related proteins in MK4MDD (count: 1)
GNAL related GO terms (count: 22)
GNAL related KEGG pathways (count: 2)
GNAL related BioCarta pathways (count: 0)
GNAL related Reactome pathways (count: 3)
GNAL related interactors from protein-protein interaction data in HPRD (count: 0)