MK4MDD

Gene Report

Basic Information
Approved Symbol PDE11A
Approved Name phosphodiesterase 11A
Location 2q31.3
Position chr2:178972981-178973066 (-)
External Links Entrez Gene: 50940
Ensembl: ENSG00000128655
UCSC: uc002ulq.3
HGNC ID: 8773
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between PDE11A and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
PDE11A Wong, 2006 patients and normal controls P-value<0.0001 In the PDE11A gene, haplotype GAACC in rs1465831-rs3770034-r...... In the PDE11A gene, haplotype GAACC in rs1465831-rs3770034-rs1866212-rs1561320-rs1370656 was found to be significantly associated with a diagnosis of depression (P < 0.0001). More...
PDE11A Luo, 2009 patients and normal controls 18 common haplotypes (with frequency higher than 0.8%) in th...... 18 common haplotypes (with frequency higher than 0.8%) in this gene have been found in the studied population. Six haplotypes showed significantly different frequencies between the MDD group and the control group. More...

Positive relationships between PDE11A and other components at different levels (count: 0) Help
Positive relationship network of PDE11A in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between PDE11A and MDD (count: 0)
Negative relationships between PDE11A and other components at different levels (count: 0) Help
PDE11A related SNPs in MK4MDD (count: 0)
PDE11A related proteins in MK4MDD (count: 0)
PDE11A related GO terms (count: 18)
PDE11A related KEGG pathways (count: 1)
PDE11A related BioCarta pathways (count: 0)
PDE11A related Reactome pathways (count: 2)
PDE11A related interactors from protein-protein interaction data in HPRD (count: 0)