MK4MDD

Gene Report

Basic Information
Approved Symbol S100A10
Approved Name S100 calcium binding protein A10
Previous Symbol ANX2LG, CAL1L
Previous Name "S100 calcium-binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11))", "S100 calcium binding protein A10 (annexin II ligand, calpactin I, light polypeptide (p11))"
Symbol Alias P11, 42C, CLP11
Name Alias "annexin II tetramer (AIIt) p11 subunit"
Location 1q21
Position chr1:151966228-151966714 (-)
External Links Entrez Gene: 6281
Ensembl: ENSG00000197747
UCSC: uc001ezl.3
HGNC ID: 10487
No. of Studies (Positive/Negative) 3(1/2) Help
Type Literature-origin; Protein mapped

Positive relationships between S100A10 and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
p11 Su, 2009 patients and normal controls We found that patients with PTSD had lower levels of p11 mRN...... We found that patients with PTSD had lower levels of p11 mRNA than control subjects, while those with MDD, BP and SCZ had significantly higher p11 levels than the controls. More...

Positive relationships between S100A10 and other components at different levels (count: 0) Help
Positive relationship network of S100A10 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between S100A10 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description
p11 Verma R, 2007 Patients and nomal controls Resequencing revealed nine novel rare variants, including a...... Resequencing revealed nine novel rare variants, including a missense mutation (Asp60Glu) observed in one case and one control, and four variants that occurred only in cases and not controls. The number of rare variants in cases did not exceed that expected by chance for the length of sequence analyzed, and also was not significantly greater than that observed in controls. Resequencing also identified two known SNPs, one (rs4845720) of which was significantly more frequent in cases than controls in the resequenced sample (3.1% vs. 0.9%, P = 0.03), though not in the larger sample (3% vs. 2%, P = 0.15). None of the tag SNPs showed any evidence of association. More...
S100A10 Tzang RF, 2008 Patients and nomal controls No significant association with MDD was discovered in single...... No significant association with MDD was discovered in single locus or haplotype analyses. More...

Negative relationships between S100A10 and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


S100A10 related SNPs in MK4MDD (count: 0)
S100A10 related proteins in MK4MDD (count: 1)
S100A10 related GO terms (count: 17)
S100A10 related KEGG pathways (count: 0)
S100A10 related BioCarta pathways (count: 0)
S100A10 related Reactome pathways (count: 0)
S100A10 related interactors from protein-protein interaction data in HPRD (count: 11)