MK4MDD

Gene Report

Basic Information
Approved Symbol GPNMB
Approved Name glycoprotein (transmembrane) nmb
Symbol Alias NMB, HGFIN
Name Alias "transmembrane glycoprotein", "glycoprotein NMB", "glycoprotein nmb-like protein", "osteoactivin"
Location 7p
Position chr7:23313844-23314729 (+)
External Links Entrez Gene: 10457
Ensembl: ENSG00000136235
UCSC: uc003swc.3
HGNC ID: 4462
No. of Studies (Positive/Negative) 1(1/0) Help
Type Literature-origin

Positive relationships between GPNMB and MDD (count: 1)
Name in Literature Reference Research Type Statistical Result Relation Description Help
GPNMB Sibille E, 2009 animal model; patients and nomal controls R=0.88, P-value<5E-6; y slope=1.11 Upregulated in MDD patients Upregulated in MDD patients

Positive relationships between GPNMB and other components at different levels (count: 0) Help
Positive relationship network of GPNMB in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between GPNMB and MDD (count: 0)
Negative relationships between GPNMB and other components at different levels (count: 0) Help
GPNMB related SNPs in MK4MDD (count: 0)
GPNMB related proteins in MK4MDD (count: 0)
GPNMB related GO terms (count: 10)
GPNMB related KEGG pathways (count: 0)
GPNMB related BioCarta pathways (count: 0)
GPNMB related Reactome pathways (count: 0)
GPNMB related interactors from protein-protein interaction data in HPRD (count: 1)