Gene Report

Basic Information

Approved Symbol	COL16A1
Approved Name	collagen, type XVI, alpha 1
Location	1p35-p34
Position	chr1:32169438-32169763 (-)
External Links	Entrez Gene: 1307 Ensembl: ENSG00000084636 UCSC: uc001btk.1 HGNC ID: 2193
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between COL16A1 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
COL16A1	Aston, 2005	patients and normal controls		Genes altered in major depressive disorder Genes altered in major depressive disorder

Positive relationships between COL16A1 and other components at different levels (count: 0)

Positive relationship network of COL16A1 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between COL16A1 and MDD (count: 0)

Negative relationships between COL16A1 and other components at different levels (count: 0)

COL16A1 related SNPs in MK4MDD (count: 0)

COL16A1 related proteins in MK4MDD (count: 0)

COL16A1 related GO terms (count: 16)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0005788	endoplasmic reticulum lumen	cellular component	TAS
GO:0005178	integrin binding	molecular function	IDA[16754661]
GO:0022617	extracellular matrix disassembly	biological process	TAS
GO:0005597	collagen type XVI trimer	cellular component	TAS[1284248]
GO:0005515	protein binding	molecular function	IPI[15165854\|16754661]
GO:0007229	integrin-mediated signaling pathway	biological process	TAS[16754661]
GO:0030574	collagen catabolic process	biological process	TAS
GO:0033627	cell adhesion mediated by integrin	biological process	IDA[16754661]
GO:0030198	extracellular matrix organization	biological process	TAS
GO:0051894	positive regulation of focal adhesion assembly	biological process	IDA[24466237]
GO:0033622	integrin activation	biological process	IDA[16754661]
GO:0005576	extracellular region	cellular component	TAS
GO:0007155	cell adhesion	biological process	IDA[16754661]
GO:0007565	female pregnancy	biological process	TAS[1284248]
GO:0005578	proteinaceous extracellular matrix	cellular component	IEA
GO:0071230	cellular response to amino acid stimulus	biological process	IEA

COL16A1 related KEGG pathways (count: 0)

COL16A1 related BioCarta pathways (count: 0)

COL16A1 related Reactome pathways (count: 0)

COL16A1 related interactors from protein-protein interaction data in HPRD (count: 0)

Gene Report

Gene mapped GO terms