MK4MDD

Gene Report

Basic Information
Approved Symbol TOB1
Approved Name transducer of ERBB2, 1
Previous Symbol TROB1
Symbol Alias TOB, TROB
Location 17q21.33
Position chr17:48945166-48945339 (-)
External Links Entrez Gene: 10140
Ensembl: ENSG00000141232
UCSC: uc002isw.3
HGNC ID: 11979
No. of Studies (Positive/Negative) 2(2/0) Help
Type Literature-origin

Positive relationships between TOB1 and MDD (count: 2)
Name in Literature Reference Research Type Statistical Result Relation Description Help
Transducer of ERBB2, 1 Tochigi, 2008 patients and normal controls Genes differentially expressed in major depression Genes differentially expressed in major depression
TOB1 Kerman IA, 2012 patients and normal controls The greatest changes in expression were observed among trans...... The greatest changes in expression were observed among transcriptional regulators, including downregulation in the expression of TOB1, EGR1, and NR4A2 and their downstream targets. More...

Positive relationships between TOB1 and other components at different levels (count: 0) Help
Positive relationship network of TOB1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between TOB1 and MDD (count: 0)
Negative relationships between TOB1 and other components at different levels (count: 0) Help
TOB1 related SNPs in MK4MDD (count: 0)
TOB1 related proteins in MK4MDD (count: 0)
TOB1 related GO terms (count: 18)
TOB1 related KEGG pathways (count: 0)
TOB1 related BioCarta pathways (count: 1)
TOB1 related Reactome pathways (count: 0)
TOB1 related interactors from protein-protein interaction data in HPRD (count: 13)