Gene Report

Basic Information

Approved Symbol	KAL1
Approved Name	Kallmann syndrome 1 sequence
Previous Symbol	KAL, ADMLX
Symbol Alias	KALIG-1, WFDC19
Name Alias	anosmin-1, "WAP four-disulfide core domain 19"
Location	Xp22.32
Position	chrX:8496915-8700227 (-)
External Links	Entrez Gene: 3730 Ensembl: ENSG00000011201 UCSC: uc004csf.3 HGNC ID: 6211
No. of Studies (Positive/Negative)	1(1/0)
Type	Literature-origin

Positive relationships between KAL1 and MDD (count: 1)

Name in Literature	Reference	Research Type	Statistical Result	Relation Description
KAL1	Aston, 2005	patients and normal controls		Genes altered in major depressive disorder Genes altered in major depressive disorder

Positive relationships between KAL1 and other components at different levels (count: 0)

Positive relationship network of KAL1 in MK4MDD

Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.

Genetic/Epigenetic Locus	Protein and Other Molecule	Cell and Molecular Pathway	Neural System	Cognition and Behavior	Symptoms and Signs	Environment	MDD

2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web

Negative relationships between KAL1 and MDD (count: 0)

Negative relationships between KAL1 and other components at different levels (count: 0)

KAL1 related SNPs in MK4MDD (count: 0)

KAL1 related proteins in MK4MDD (count: 1)

Approved Name	UniportKB	No. of Studies (Positive/Negative)	Source
Anosmin-1	P23352	0(0/0)	Gene mapped

KAL1 related GO terms (count: 11)

ID	Name	Type	Evidence
Gene mapped GO terms
GO:0005615	extracellular space	cellular component	TAS[8842728]
GO:0007155	cell adhesion	biological process	IEA
GO:0006928	cellular component movement	biological process	TAS[1922361]
GO:0008201	heparin binding	molecular function	IEA
GO:0005886	plasma membrane	cellular component	IEA
GO:0005578	proteinaceous extracellular matrix	cellular component	TAS[8832397]
GO:0007411	axon guidance	biological process	TAS[1922361]
GO:0005201	extracellular matrix structural constituent	molecular function	TAS[8842728]
GO:0006935	chemotaxis	biological process	TAS[8842728]
GO:0004867	serine-type endopeptidase inhibitor activity	molecular function	IEA
GO:0005515	protein binding	molecular function	IPI[19696444]

KAL1 related KEGG pathways (count: 0)

KAL1 related BioCarta pathways (count: 0)

KAL1 related Reactome pathways (count: 0)

KAL1 related interactors from protein-protein interaction data in HPRD (count: 1)

Gene Report

Gene mapped GO terms