MK4MDD

Gene Report

Basic Information
Approved Symbol FGFR1
Approved Name fibroblast growth factor receptor 1
Previous Symbol FLT2, KAL2
Previous Name "fms-related tyrosine kinase 2"
Symbol Alias H2, H3, H4, H5, CEK, FLG, BFGFR, N-SAM, CD331
Name Alias "Pfeiffer syndrome"
Location 8p12
Position chr8:38325499-38326352 (-)
External Links Entrez Gene: 2260
Ensembl: ENSG00000077782
UCSC: uc011lbu.2
HGNC ID: 3688
No. of Studies (Positive/Negative) 4(4/0) Help
Type Literature-origin

Positive relationships between FGFR1 and MDD (count: 3)
Name in Literature Reference Research Type Statistical Result Relation Description Help
FGFR1 Gaughran, 2006 patients and normal controls The percentage of FGFR1 mRNA+ cells was higher in depression...... The percentage of FGFR1 mRNA+ cells was higher in depression (CA1 and CA4) and schizophrenia (CA4) than in controls. FGFR1 mRNA expression was higher in depression than in the other groups in CA1, CA4 and DG. More...
Fibroblast growth factor receptor 1 Tochigi, 2008 patients and normal controls Genes differentially expressed in major depression Genes differentially expressed in major depression
FGFR-1 Goswami DB, 2013 patients and normal controls P-value=0.01 Setting our cutoff p-value Setting our cutoff p-value More...

Positive relationships between FGFR1 and other components at different levels (count: 1) Help
Genetic/epigenetic locus   Protein and other molecule   Cell and molecular pathway   Neural system   Cognition and behavior   Symptoms and signs   Environment
SNP Gene Region Epigenetic site Protein Molecule Pathway Cell Neurobiological system Brain morphology and function Cognition and behavior Symptoms Signs Environment


Positive relationship network of FGFR1 in MK4MDD
Network loading ...

Note:
1. The different color of the nodes denotes the level of the nodes.
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
Genetic/Epigenetic Locus Protein and Other Molecule Cell and Molecular Pathway Neural System Cognition and Behavior Symptoms and Signs Environment MDD
2. Besides the component related relationships from literature, gene mapped protein and protein mapped gene are also shown in the network. If the mapped gene or protein is not from literature, square node would be used instead of Circle node. Accordingly, the relationship is marked with dot line.
2. User can drag the nodes to rearrange the layout of the network. Click the node will enter the report page of the node. Right-click will show also the menus to link to the report page of the node and remove the node and related edges. Hover the node will show the level of the node and hover the edge will show the evidence/description of the edge.
3. The network is generated using Cytoscape Web Cytoscape Web
Negative relationships between FGFR1 and MDD (count: 0)
Negative relationships between FGFR1 and other components at different levels (count: 0) Help
FGFR1 related SNPs in MK4MDD (count: 0)
FGFR1 related proteins in MK4MDD (count: 0)
FGFR1 related GO terms (count: 84)
FGFR1 related KEGG pathways (count: 6)
FGFR1 related BioCarta pathways (count: 0)
FGFR1 related Reactome pathways (count: 9)
FGFR1 related interactors from protein-protein interaction data in HPRD (count: 38)